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Year Number of Results
2014 2
2015 1
2018 1
2019 2
2020 2
2021 1
2023 1
2024 0

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Page 1
Validation study of German inpatient administrative health data for epidemiological surveillance and measurement of quality of care for sepsis: the OPTIMISE study protocol.
Schwarzkopf D, Fleischmann-Struzek C, Schlattmann P, Dorow H, Ouart D, Edel A, Gonnert FA, Götz J, Gründling M, Heim M, Jaschinski U, Lindau S, Meybohm P, Putensen C, Sander M, Reinhart K; OPTIMISE study group. Schwarzkopf D, et al. BMJ Open. 2020 Oct 5;10(10):e035763. doi: 10.1136/bmjopen-2019-035763. BMJ Open. 2020. PMID: 33020079 Free PMC article.
Symptom Remission and Brain Cortical Networks at First Clinical Presentation of Psychosis: The OPTiMiSE Study.
Dazzan P, Lawrence AJ, Reinders AATS, Egerton A, van Haren NEM, Merritt K, Barker GJ, Perez-Iglesias R, Sendt KV, Demjaha A, Nam KW, Sommer IE, Pantelis C, Wolfgang Fleischhacker W, van Rossum IW, Galderisi S, Mucci A, Drake R, Lewis S, Weiser M, Martinez Diaz-Caneja CM, Janssen J, Diaz-Marsa M, Rodríguez-Jimenez R, Arango C, Baandrup L, Broberg B, Rostrup E, Ebdrup BH, Glenthøj B, Kahn RS, McGuire P; OPTiMiSE study group. Dazzan P, et al. Schizophr Bull. 2021 Mar 16;47(2):444-455. doi: 10.1093/schbul/sbaa115. Schizophr Bull. 2021. PMID: 33057670 Free PMC article. Clinical Trial.
Stratification and prediction of remission in first-episode psychosis patients: the OPTiMiSE cohort study.
Martinuzzi E, Barbosa S, Daoudlarian D, Bel Haj Ali W, Gilet C, Fillatre L, Khalfallah O, Troudet R, Jamain S, Fond G, Sommer I, Leucht S, Dazzan P, McGuire P, Arango C, Diaz-Caneja CM, Fleischhacker W, Rujescu D, Glenthøj B, Winter I, Kahn RS, Yolken R, Lewis S, Drake R, Davidovic L, Leboyer M, Glaichenhaus N; OPTiMiSE Study Group. Martinuzzi E, et al. Transl Psychiatry. 2019 Jan 17;9(1):20. doi: 10.1038/s41398-018-0366-5. Transl Psychiatry. 2019. PMID: 30655509 Free PMC article. Clinical Trial.
Amisulpride and olanzapine followed by open-label treatment with clozapine in first-episode schizophrenia and schizophreniform disorder (OPTiMiSE): a three-phase switching study.
Kahn RS, Winter van Rossum I, Leucht S, McGuire P, Lewis SW, Leboyer M, Arango C, Dazzan P, Drake R, Heres S, Díaz-Caneja CM, Rujescu D, Weiser M, Galderisi S, Glenthøj B, Eijkemans MJC, Fleischhacker WW, Kapur S, Sommer IE; OPTiMiSE study group. Kahn RS, et al. Lancet Psychiatry. 2018 Oct;5(10):797-807. doi: 10.1016/S2215-0366(18)30252-9. Epub 2018 Aug 13. Lancet Psychiatry. 2018. PMID: 30115598 Clinical Trial.
Gene expression and response prediction to amisulpride in the OPTiMiSE first episode psychoses.
Troudet R, Ali WBH, Bacq-Daian D, Rossum IWV, Boland-Auge A, Battail C, Barau C; OPTiMiSE study group; Rujescu D, McGuire P, Kahn RS, Deleuze JF, Leboyer M, Jamain S. Troudet R, et al. Neuropsychopharmacology. 2020 Sep;45(10):1637-1644. doi: 10.1038/s41386-020-0703-2. Epub 2020 May 25. Neuropsychopharmacology. 2020. PMID: 32450569 Free PMC article.
Correction: Stratification and prediction of remission in first-episode psychosis patients: the OPTiMiSE cohort study.
Martinuzzi E, Barbosa S, Daoudlarian D, Ali WBH, Gilet C, Fillatre L, Khalfallah O, Troudet R, Jamain S, Fond G, Sommer I, Leucht S, Dazzan P, McGuire P, Arango C, Diaz-Caneja CM, Fleischhacker W, Rujescu D, Glenthøj B, Winter I, Kahn RS, Yolken R, Lewis S, Drake R, Davidovic L, Leboyer M, Glaichenhaus N; OPTiMiSE Study Group. Martinuzzi E, et al. Transl Psychiatry. 2019 Jun 21;9(1):171. doi: 10.1038/s41398-019-0505-7. Transl Psychiatry. 2019. PMID: 31227688 Free PMC article.
Effect of a perioperative, cardiac output-guided hemodynamic therapy algorithm on outcomes following major gastrointestinal surgery: a randomized clinical trial and systematic review.
Pearse RM, Harrison DA, MacDonald N, Gillies MA, Blunt M, Ackland G, Grocott MP, Ahern A, Griggs K, Scott R, Hinds C, Rowan K; OPTIMISE Study Group. Pearse RM, et al. JAMA. 2014 Jun 4;311(21):2181-90. doi: 10.1001/jama.2014.5305. JAMA. 2014. PMID: 24842135 Clinical Trial.