O'Sullivan D - Search Results

1

Mitochondrial genome-knockout cells demonstrate a dual mechanism of action for the electron transport complex I inhibitor mycothiazole.

Meyer KJ, Singh AJ, Cameron A, Tan AS, Leahy DC, O'Sullivan D, Joshi P, La Flamme AC, Northcote PT, Berridge MV, Miller JH. Meyer KJ, et al. Mar Drugs. 2012 Apr;10(4):900-917. doi: 10.3390/md10040900. Epub 2012 Apr 16. Mar Drugs. 2012. PMID: 22690150 Free PMC article.

2

Delaying the onset of experimental autoimmune encephalomyelitis with the microtubule-stabilizing compounds, paclitaxel and Peloruside A.

Crume KP, O'Sullivan D, Miller JH, Northcote PT, La Flamme AC. Crume KP, et al. J Leukoc Biol. 2009 Oct;86(4):949-58. doi: 10.1189/jlb.0908541. Epub 2009 Aug 4. J Leukoc Biol. 2009. PMID: 19654226

3

Synergistic interactions between peloruside A and other microtubule-stabilizing and destabilizing agents in cultured human ovarian carcinoma cells and murine T cells.

Wilmes A, O'Sullivan D, Chan A, Chandrahasen C, Paterson I, Northcote PT, La Flamme AC, Miller JH. Wilmes A, et al. Cancer Chemother Pharmacol. 2011 Jul;68(1):117-26. doi: 10.1007/s00280-010-1461-3. Epub 2010 Sep 17. Cancer Chemother Pharmacol. 2011. PMID: 20848285

4

Microtubule-stabilizing agents delay the onset of EAE through inhibition of migration.

O'Sullivan D, Miller JH, Northcote PT, La Flamme AC. O'Sullivan D, et al. Immunol Cell Biol. 2013 Oct;91(9):583-92. doi: 10.1038/icb.2013.47. Epub 2013 Sep 24. Immunol Cell Biol. 2013. PMID: 24060965

5

Protection from EAE by IL-4Ralpha(-/-) macrophages depends upon T regulatory cell involvement.

Keating P, O'Sullivan D, Tierney JB, Kenwright D, Miromoeini S, Mawasse L, Brombacher F, La Flamme AC. Keating P, et al. Immunol Cell Biol. 2009 Oct;87(7):534-45. doi: 10.1038/icb.2009.37. Epub 2009 Jun 2. Immunol Cell Biol. 2009. PMID: 19488061

6

Targeting innate receptors with MIS416 reshapes Th responses and suppresses CNS disease in a mouse model of multiple sclerosis.

White M, Webster G, O'Sullivan D, Stone S, La Flamme AC. White M, et al. PLoS One. 2014 Jan 31;9(1):e87712. doi: 10.1371/journal.pone.0087712. eCollection 2014. PLoS One. 2014. PMID: 24498172 Free PMC article.

7

Treatment with the antipsychotic agent, risperidone, reduces disease severity in experimental autoimmune encephalomyelitis.

O'Sullivan D, Green L, Stone S, Zareie P, Kharkrang M, Fong D, Connor B, La Flamme AC. O'Sullivan D, et al. PLoS One. 2014 Aug 12;9(8):e104430. doi: 10.1371/journal.pone.0104430. eCollection 2014. PLoS One. 2014. PMID: 25116424 Free PMC article.

8

Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation.

Puleston DJ, Buck MD, Klein Geltink RI, Kyle RL, Caputa G, O'Sullivan D, Cameron AM, Castoldi A, Musa Y, Kabat AM, Zhang Y, Flachsmann LJ, Field CS, Patterson AE, Scherer S, Alfei F, Baixauli F, Austin SK, Kelly B, Matsushita M, Curtis JD, Grzes KM, Villa M, Corrado M, Sanin DE, Qiu J, Pällman N, Paz K, Maccari ME, Blazar BR, Mittler G, Buescher JM, Zehn D, Rospert S, Pearce EJ, Balabanov S, Pearce EL. Puleston DJ, et al. Cell Metab. 2019 Aug 6;30(2):352-363.e8. doi: 10.1016/j.cmet.2019.05.003. Epub 2019 May 23. Cell Metab. 2019. PMID: 31130465 Free PMC article.

9

Mitochondrial Membrane Potential Regulates Nuclear Gene Expression in Macrophages Exposed to Prostaglandin E2.

Sanin DE, Matsushita M, Klein Geltink RI, Grzes KM, van Teijlingen Bakker N, Corrado M, Kabat AM, Buck MD, Qiu J, Lawless SJ, Cameron AM, Villa M, Baixauli F, Patterson AE, Hässler F, Curtis JD, O'Neill CM, O'Sullivan D, Wu D, Mittler G, Huang SC, Pearce EL, Pearce EJ. Sanin DE, et al. Immunity. 2018 Dec 18;49(6):1021-1033.e6. doi: 10.1016/j.immuni.2018.10.011. Immunity. 2018. PMID: 30566880 Free PMC article.

10

Glucose makes T_reg lose their temper.

Villa M, O'Sullivan D, Pearce EL. Villa M, et al. Cancer Cell. 2021 Apr 12;39(4):460-462. doi: 10.1016/j.ccell.2021.03.001. Cancer Cell. 2021. PMID: 33848476 Free article.

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