O'Prey J - Search Results

1

mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid Efflux.

Beaumatin F, O'Prey J, Barthet VJA, Zunino B, Parvy JP, Bachmann AM, O'Prey M, Kania E, Gonzalez PS, Macintosh R, Lao LY, Nixon C, Lopez J, Long JS, Tait SWG, Ryan KM. Beaumatin F, et al. Among authors: o prey j. Mol Cell. 2019 Oct 3;76(1):163-176.e8. doi: 10.1016/j.molcel.2019.07.021. Epub 2019 Sep 3. Mol Cell. 2019. PMID: 31492633 Free PMC article.

2

DRAM-4 and DRAM-5 are compensatory regulators of autophagy and cell survival in nutrient-deprived conditions.

Barthet VJA, Mrschtik M, Kania E, McEwan DG, Croft D, O'Prey J, Long JS, Ryan KM. Barthet VJA, et al. Among authors: o prey j. FEBS J. 2022 Jul;289(13):3752-3769. doi: 10.1111/febs.16365. Epub 2022 Feb 4. FEBS J. 2022. PMID: 35060334 Free PMC article.

3

DRAM-3 modulates autophagy and promotes cell survival in the absence of glucose.

Mrschtik M, O'Prey J, Lao LY, Long JS, Beaumatin F, Strachan D, O'Prey M, Skommer J, Ryan KM. Mrschtik M, et al. Cell Death Differ. 2015 Oct;22(10):1714-26. doi: 10.1038/cdd.2015.26. Epub 2015 May 1. Cell Death Differ. 2015. PMID: 25929859 Free PMC article.

4

Extracellular adenosine sensing-a metabolic cell death priming mechanism downstream of p53.

Long JS, Crighton D, O'Prey J, Mackay G, Zheng L, Palmer TM, Gottlieb E, Ryan KM. Long JS, et al. Mol Cell. 2013 May 9;50(3):394-406. doi: 10.1016/j.molcel.2013.03.016. Epub 2013 Apr 18. Mol Cell. 2013. PMID: 23603120 Free article.

5

mTORC1-independent autophagy regulates receptor tyrosine kinase phosphorylation in colorectal cancer cells via an mTORC2-mediated mechanism.

Lampada A, O'Prey J, Szabadkai G, Ryan KM, Hochhauser D, Salomoni P. Lampada A, et al. Cell Death Differ. 2017 Jun;24(6):1045-1062. doi: 10.1038/cdd.2017.41. Epub 2017 May 5. Cell Death Differ. 2017. PMID: 28475179 Free PMC article.

6

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis.

Crighton D, Wilkinson S, O'Prey J, Syed N, Smith P, Harrison PR, Gasco M, Garrone O, Crook T, Ryan KM. Crighton D, et al. Cell. 2006 Jul 14;126(1):121-34. doi: 10.1016/j.cell.2006.05.034. Cell. 2006. PMID: 16839881 Free article.

7

Analysis of DRAM-related proteins reveals evolutionarily conserved and divergent roles in the control of autophagy.

O'Prey J, Skommer J, Wilkinson S, Ryan KM. O'Prey J, et al. Cell Cycle. 2009 Jul 15;8(14):2260-5. doi: 10.4161/cc.8.14.9050. Epub 2009 Jul 19. Cell Cycle. 2009. PMID: 19556885 Free article.

8

DRAM-1 encodes multiple isoforms that regulate autophagy.

Mah LY, O'Prey J, Baudot AD, Hoekstra A, Ryan KM. Mah LY, et al. Autophagy. 2012 Jan;8(1):18-28. doi: 10.4161/auto.8.1.18077. Epub 2012 Jan 1. Autophagy. 2012. PMID: 22082963 Free PMC article.

9

Loss of autophagy causes a synthetic lethal deficiency in DNA repair.

Liu EY, Xu N, O'Prey J, Lao LY, Joshi S, Long JS, O'Prey M, Croft DR, Beaumatin F, Baudot AD, Mrschtik M, Rosenfeldt M, Zhang Y, Gillespie DA, Ryan KM. Liu EY, et al. Proc Natl Acad Sci U S A. 2015 Jan 20;112(3):773-8. doi: 10.1073/pnas.1409563112. Epub 2015 Jan 7. Proc Natl Acad Sci U S A. 2015. PMID: 25568088 Free PMC article.

10

Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function.

Sakamaki JI, Wilkinson S, Hahn M, Tasdemir N, O'Prey J, Clark W, Hedley A, Nixon C, Long JS, New M, Van Acker T, Tooze SA, Lowe SW, Dikic I, Ryan KM. Sakamaki JI, et al. Mol Cell. 2017 May 18;66(4):517-532.e9. doi: 10.1016/j.molcel.2017.04.027. Mol Cell. 2017. PMID: 28525743 Free PMC article.

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