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Concussion susceptibility is mediated by spreading depolarization-induced neurovascular dysfunction.
Parker E, Aboghazleh R, Mumby G, Veksler R, Ofer J, Newton J, Smith R, Kamintsky L, Jones CMA, O'Keeffe E, Kelly E, Doelle K, Roach I, Yang LT, Moradi P, Lin JM, Gleason AJ, Atkinson C, Bowen C, Brewer KD, Doherty CP, Campbell M, Clarke DB, van Hameren G, Kaufer D, Friedman A. Parker E, et al. Among authors: o keeffe e. Brain. 2022 Jun 30;145(6):2049-2063. doi: 10.1093/brain/awab450. Brain. 2022. PMID: 34927674 Free PMC article.
Dynamic Blood-Brain Barrier Regulation in Mild Traumatic Brain Injury.
O'Keeffe E, Kelly E, Liu Y, Giordano C, Wallace E, Hynes M, Tiernan S, Meagher A, Greene C, Hughes S, Burke T, Kealy J, Doyle N, Hay A, Farrell M, Grant GA, Friedman A, Veksler R, Molloy MG, Meaney JF, Pender N, Camarillo D, Doherty CP, Campbell M. O'Keeffe E, et al. J Neurotrauma. 2020 Jan 15;37(2):347-356. doi: 10.1089/neu.2019.6483. Epub 2019 Nov 8. J Neurotrauma. 2020. PMID: 31702476 Free PMC article.
Multi-Directional Dynamic Model for Traumatic Brain Injury Detection.
Laksari K, Fanton M, Wu LC, Nguyen TH, Kurt M, Giordano C, Kelly E, O'Keeffe E, Wallace E, Doherty C, Campbell M, Tiernan S, Grant G, Ruan J, Barbat S, Camarillo DB. Laksari K, et al. J Neurotrauma. 2020 Apr 1;37(7):982-993. doi: 10.1089/neu.2018.6340. Epub 2020 Feb 4. J Neurotrauma. 2020. PMID: 31856650 Free PMC article.
Slow blood-to-brain transport underlies enduring barrier dysfunction in American football players.
Veksler R, Vazana U, Serlin Y, Prager O, Ofer J, Shemen N, Fisher AM, Minaeva O, Hua N, Saar-Ashkenazy R, Benou I, Riklin-Raviv T, Parker E, Mumby G, Kamintsky L, Beyea S, Bowen CV, Shelef I, O'Keeffe E, Campbell M, Kaufer D, Goldstein LE, Friedman A. Veksler R, et al. Among authors: o keeffe e. Brain. 2020 Jun 1;143(6):1826-1842. doi: 10.1093/brain/awaa140. Brain. 2020. PMID: 32464655 Free PMC article.
Concussion and the severity of head impacts in mixed martial arts.
Tiernan S, Meagher A, O'Sullivan D, O'Keeffe E, Kelly E, Wallace E, Doherty CP, Campbell M, Liu Y, Domel AG. Tiernan S, et al. Among authors: o keeffe e. Proc Inst Mech Eng H. 2020 Dec;234(12):1472-1483. doi: 10.1177/0954411920947850. Epub 2020 Aug 16. Proc Inst Mech Eng H. 2020. PMID: 32799750 Free PMC article.
Attenuated CSF-1R signalling drives cerebrovascular pathology.
Delaney C, Farrell M, Doherty CP, Brennan K, O'Keeffe E, Greene C, Byrne K, Kelly E, Birmingham N, Hickey P, Cronin S, Savvides SN, Doyle SL, Campbell M. Delaney C, et al. Among authors: o keeffe e. EMBO Mol Med. 2021 Feb 5;13(2):e12889. doi: 10.15252/emmm.202012889. Epub 2020 Dec 22. EMBO Mol Med. 2021. PMID: 33350588 Free PMC article.
Microvascular stabilization via blood-brain barrier regulation prevents seizure activity.
Greene C, Hanley N, Reschke CR, Reddy A, Mäe MA, Connolly R, Behan C, O'Keeffe E, Bolger I, Hudson N, Delaney C, Farrell MA, O'Brien DF, Cryan J, Brett FM, Beausang A, Betsholtz C, Henshall DC, Doherty CP, Campbell M. Greene C, et al. Among authors: o keeffe e. Nat Commun. 2022 Apr 14;13(1):2003. doi: 10.1038/s41467-022-29657-y. Nat Commun. 2022. PMID: 35422069 Free PMC article.
24 results