O'Donnell PA - Search Results

1

Neonatal gene therapy with a gamma retroviral vector in mucopolysaccharidosis VI cats.

Ponder KP, O'Malley TM, Wang P, O'Donnell PA, Traas AM, Knox VW, Aguirre GA, Ellinwood NM, Metcalf JA, Wang B, Parkinson-Lawrence EJ, Sleeper MM, Brooks DA, Hopwood JJ, Haskins ME. Ponder KP, et al. Among authors: o donnell pa. Mol Ther. 2012 May;20(5):898-907. doi: 10.1038/mt.2012.9. Epub 2012 Mar 6. Mol Ther. 2012. PMID: 22395531 Free PMC article.

2

Transduction of hepatocytes after neonatal delivery of a Moloney murine leukemia virus based retroviral vector results in long-term expression of beta-glucuronidase in mucopolysaccharidosis VII dogs.

Xu L, Haskins ME, Melniczek JR, Gao C, Weil MA, O'Malley TM, O'Donnell PA, Mazrier H, Ellinwood NM, Zweigle J, Wolfe JH, Ponder KP. Xu L, et al. Mol Ther. 2002 Feb;5(2):141-53. doi: 10.1006/mthe.2002.0527. Mol Ther. 2002. PMID: 11829521 Free article.

3

Therapeutic neonatal hepatic gene therapy in mucopolysaccharidosis VII dogs.

Ponder KP, Melniczek JR, Xu L, Weil MA, O'Malley TM, O'Donnell PA, Knox VW, Aguirre GD, Mazrier H, Ellinwood NM, Sleeper M, Maguire AM, Volk SW, Mango RL, Zweigle J, Wolfe JH, Haskins ME. Ponder KP, et al. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13102-7. doi: 10.1073/pnas.192353499. Epub 2002 Sep 13. Proc Natl Acad Sci U S A. 2002. PMID: 12232044 Free PMC article.

4

Expression in blood cells may contribute to biochemical and pathological improvements after neonatal intravenous gene therapy for mucopolysaccharidosis VII in dogs.

Wang B, O'Malley TM, Xu L, Vite C, Wang P, O'Donnell PA, Ellinwood NM, Haskins ME, Ponder KP. Wang B, et al. Mol Genet Metab. 2006 Jan;87(1):8-21. doi: 10.1016/j.ymgme.2005.08.014. Epub 2005 Nov 7. Mol Genet Metab. 2006. PMID: 16275036

5

Mucopolysaccharidosis I cats mount a cytotoxic T lymphocyte response after neonatal gene therapy that can be blocked with CTLA4-Ig.

Ponder KP, Wang B, Wang P, Ma X, Herati R, Wang B, Cullen K, O'Donnell P, Ellinwood NM, Traas A, Primeau TM, Haskins ME. Ponder KP, et al. Mol Ther. 2006 Jul;14(1):5-13. doi: 10.1016/j.ymthe.2006.03.015. Epub 2006 May 12. Mol Ther. 2006. PMID: 16698321 Free article.

6

Immune response after neonatal transfer of a human factor IX-expressing retroviral vector in dogs, cats, and mice.

Xu L, Mei M, Haskins ME, Nichols TC, O'donnell P, Cullen K, Dillow A, Bellinger D, Ponder KP. Xu L, et al. Thromb Res. 2007;120(2):269-80. doi: 10.1016/j.thromres.2006.09.010. Epub 2006 Nov 7. Thromb Res. 2007. PMID: 17095052

7

Correction of clinical manifestations of canine mucopolysaccharidosis I with neonatal retroviral vector gene therapy.

Traas AM, Wang P, Ma X, Tittiger M, Schaller L, O'donnell P, Sleeper MM, Vite C, Herati R, Aguirre GD, Haskins M, Ponder KP. Traas AM, et al. Mol Ther. 2007 Aug;15(8):1423-31. doi: 10.1038/sj.mt.6300201. Epub 2007 May 22. Mol Ther. 2007. PMID: 17519893 Free article.

8

Clinical, electrophysiological, and serum biochemical measures of progressive neurological and hepatic dysfunction in feline Niemann-Pick type C disease.

Vite CH, Ding W, Bryan C, O'Donnell P, Cullen K, Aleman D, Haskins ME, Van Winkle T. Vite CH, et al. Pediatr Res. 2008 Nov;64(5):544-9. doi: 10.1203/PDR.0b013e318184d2ce. Pediatr Res. 2008. PMID: 18614965 Free PMC article.

9

Radiographic evaluation of bones and joints in mucopolysaccharidosis I and VII dogs after neonatal gene therapy.

Herati RS, Knox VW, O'Donnell P, D'Angelo M, Haskins ME, Ponder KP. Herati RS, et al. Mol Genet Metab. 2008 Nov;95(3):142-51. doi: 10.1016/j.ymgme.2008.07.003. Epub 2008 Aug 15. Mol Genet Metab. 2008. PMID: 18707908 Free PMC article.

10

Upregulation of elastase activity in aorta in mucopolysaccharidosis I and VII dogs may be due to increased cytokine expression.

Metcalf JA, Linders B, Wu S, Bigg P, O'Donnell P, Sleeper MM, Whyte MP, Haskins M, Ponder KP. Metcalf JA, et al. Mol Genet Metab. 2010 Apr;99(4):396-407. doi: 10.1016/j.ymgme.2009.12.003. Epub 2009 Dec 11. Mol Genet Metab. 2010. PMID: 20044292 Free PMC article.

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