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Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.
Demenais F, Margaritte-Jeannin P, Barnes KC, Cookson WOC, Altmüller J, Ang W, Barr RG, Beaty TH, Becker AB, Beilby J, Bisgaard H, Bjornsdottir US, Bleecker E, Bønnelykke K, Boomsma DI, Bouzigon E, Brightling CE, Brossard M, Brusselle GG, Burchard E, Burkart KM, Bush A, Chan-Yeung M, Chung KF, Couto Alves A, Curtin JA, Custovic A, Daley D, de Jongste JC, Del-Rio-Navarro BE, Donohue KM, Duijts L, Eng C, Eriksson JG, Farrall M, Fedorova Y, Feenstra B, Ferreira MA; Australian Asthma Genetics Consortium (AAGC) collaborators; Freidin MB, Gajdos Z, Gauderman J, Gehring U, Geller F, Genuneit J, Gharib SA, Gilliland F, Granell R, Graves PE, Gudbjartsson DF, Haahtela T, Heckbert SR, Heederik D, Heinrich J, Heliövaara M, Henderson J, Himes BE, Hirose H, Hirschhorn JN, Hofman A, Holt P, Hottenga J, Hudson TJ, Hui J, Imboden M, Ivanov V, Jaddoe VWV, James A, Janson C, Jarvelin MR, Jarvis D, Jones G, Jonsdottir I, Jousilahti P, Kabesch M, Kähönen M, Kantor DB, Karunas AS, Khusnutdinova E, Koppelman GH, Kozyrskyj AL, Kreiner E, Kubo M, Kumar R, Kumar A, Kuokkanen M, Lahousse L, Laitinen T, Laprise C, Lathrop M, Lau S, Lee YA, Lehtimäki T, Letort S, Levin AM, Li G, Liang L, Loehr LR, London SJ, L… See abstract for full author list ➔ Demenais F, et al. Nat Genet. 2018 Jan;50(1):42-53. doi: 10.1038/s41588-017-0014-7. Epub 2017 Dec 22. Nat Genet. 2018. PMID: 29273806 Free PMC article.
Association of asthma with a functional promoter polymorphism in the IL16 gene.
Burkart KM, Barton SJ, Holloway JW, Yang IA, Cakebread JA, Cruikshank W, Little F, Jin X, Farrer LA, Clough JB, Keith TP, Holgate S, Center DM, O'Connor GT. Burkart KM, et al. J Allergy Clin Immunol. 2006 Jan;117(1):86-91. doi: 10.1016/j.jaci.2005.10.011. J Allergy Clin Immunol. 2006. PMID: 16387589
The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports.
Cupples LA, Arruda HT, Benjamin EJ, D'Agostino RB Sr, Demissie S, DeStefano AL, Dupuis J, Falls KM, Fox CS, Gottlieb DJ, Govindaraju DR, Guo CY, Heard-Costa NL, Hwang SJ, Kathiresan S, Kiel DP, Laramie JM, Larson MG, Levy D, Liu CY, Lunetta KL, Mailman MD, Manning AK, Meigs JB, Murabito JM, Newton-Cheh C, O'Connor GT, O'Donnell CJ, Pandey M, Seshadri S, Vasan RS, Wang ZY, Wilk JB, Wolf PA, Yang Q, Atwood LD. Cupples LA, et al. BMC Med Genet. 2007;8 Suppl 1(Suppl 1):S1. doi: 10.1186/1471-2350-8-S1-S1. BMC Med Genet. 2007. PMID: 17903291 Free PMC article.
Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.
Himes BE, Hunninghake GM, Baurley JW, Rafaels NM, Sleiman P, Strachan DP, Wilk JB, Willis-Owen SA, Klanderman B, Lasky-Su J, Lazarus R, Murphy AJ, Soto-Quiros ME, Avila L, Beaty T, Mathias RA, Ruczinski I, Barnes KC, Celedón JC, Cookson WO, Gauderman WJ, Gilliland FD, Hakonarson H, Lange C, Moffatt MF, O'Connor GT, Raby BA, Silverman EK, Weiss ST. Himes BE, et al. Am J Hum Genet. 2009 May;84(5):581-93. doi: 10.1016/j.ajhg.2009.04.006. Epub 2009 May 7. Am J Hum Genet. 2009. PMID: 19426955 Free PMC article.
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function.
Hancock DB, Eijgelsheim M, Wilk JB, Gharib SA, Loehr LR, Marciante KD, Franceschini N, van Durme YM, Chen TH, Barr RG, Schabath MB, Couper DJ, Brusselle GG, Psaty BM, van Duijn CM, Rotter JI, Uitterlinden AG, Hofman A, Punjabi NM, Rivadeneira F, Morrison AC, Enright PL, North KE, Heckbert SR, Lumley T, Stricker BH, O'Connor GT, London SJ. Hancock DB, et al. Nat Genet. 2010 Jan;42(1):45-52. doi: 10.1038/ng.500. Epub 2009 Dec 13. Nat Genet. 2010. PMID: 20010835 Free PMC article.
PDE11A associations with asthma: results of a genome-wide association scan.
DeWan AT, Triche EW, Xu X, Hsu LI, Zhao C, Belanger K, Hellenbrand K, Willis-Owen SA, Moffatt M, Cookson WO, Himes BE, Weiss ST, Gauderman WJ, Baurley JW, Gilliland F, Wilk JB, O'Connor GT, Strachan DP, Hoh J, Bracken MB. DeWan AT, et al. J Allergy Clin Immunol. 2010 Oct;126(4):871-873.e9. doi: 10.1016/j.jaci.2010.06.051. J Allergy Clin Immunol. 2010. PMID: 20920776 Free PMC article. No abstract available.
469 results