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USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma.
Ruiz EJ, Pinto-Fernandez A, Turnbull AP, Lan L, Charlton TM, Scott HC, Damianou A, Vere G, Riising EM, Da Costa C, Krajewski WW, Guerin D, Kearns JD, Ioannidis S, Katz M, McKinnon C, O'Connell J, Moncaut N, Rosewell I, Nye E, Jones N, Heride C, Gersch M, Wu M, Dinsmore CJ, Hammonds TR, Kim S, Komander D, Urbe S, Clague MJ, Kessler BM, Behrens A. Ruiz EJ, et al. Among authors: nye e. Elife. 2021 Oct 12;10:e71596. doi: 10.7554/eLife.71596. Elife. 2021. PMID: 34636321 Free PMC article.
The F-box protein Fbw7 is required for cerebellar development.
Jandke A, Da Costa C, Sancho R, Nye E, Spencer-Dene B, Behrens A. Jandke A, et al. Among authors: nye e. Dev Biol. 2011 Oct 1;358(1):201-12. doi: 10.1016/j.ydbio.2011.07.030. Epub 2011 Jul 29. Dev Biol. 2011. PMID: 21827743 Free article.
YAP drives cutaneous squamous cell carcinoma formation and progression.
Vincent-Mistiaen Z, Elbediwy A, Vanyai H, Cotton J, Stamp G, Nye E, Spencer-Dene B, Thomas GJ, Mao J, Thompson B. Vincent-Mistiaen Z, et al. Among authors: nye e. Elife. 2018 Sep 20;7:e33304. doi: 10.7554/eLife.33304. Elife. 2018. PMID: 30231971 Free PMC article.
ATMIN Is a Tumor Suppressor Gene in Lung Adenocarcinoma.
Foster H, Ruiz EJ, Moore C, Stamp GWH, Nye EL, Li N, Pan Y, He Y, Downward J, Behrens A. Foster H, et al. Among authors: nye el. Cancer Res. 2019 Oct 15;79(20):5159-5166. doi: 10.1158/0008-5472.CAN-19-0647. Epub 2019 Sep 3. Cancer Res. 2019. PMID: 31481498 Free PMC article.
251 results