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MEK inhibition overcomes chemoimmunotherapy resistance by inducing CXCL10 in cancer cells.
Cancer Cell. 2022 Feb 14;40(2):136-152.e12. doi: 10.1016/j.ccell.2021.12.009. Epub 2022 Jan 19.
Cancer Cell. 2022.
PMID: 35051357
Free article.
Trifluridine/Tipiracil plus Oxaliplatin Improves PD-1 Blockade in Colorectal Cancer by Inducing Immunogenic Cell Death and Depleting Macrophages.
Limagne E, Thibaudin M, Nuttin L, Spill A, Derangère V, Fumet JD, Amellal N, Peranzoni E, Cattan V, Ghiringhelli F.
Limagne E, et al. Among authors: nuttin l.
Cancer Immunol Res. 2019 Dec;7(12):1958-1969. doi: 10.1158/2326-6066.CIR-19-0228. Epub 2019 Oct 14.
Cancer Immunol Res. 2019.
PMID: 31611243
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Association of Anti-EGFR Antibody and MEK Inhibitor in Gynecological Cancer Harboring RAS Mutation: A Case Series.
Niogret J, Derangère V, Richard C, Nuttin L, Ghiringhelli F, Favier L, Lefevre LB, Bergeron A, Arnould L, Boidot R.
Niogret J, et al. Among authors: nuttin l.
Int J Mol Sci. 2022 Mar 19;23(6):3343. doi: 10.3390/ijms23063343.
Int J Mol Sci. 2022.
PMID: 35328764
Free PMC article.
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Development of a successful antitumor therapeutic model combining in vivo dendritic cell vaccination with tumor irradiation and intratumoral GM-CSF delivery.
Driessens G, Nuttin L, Gras A, Maetens J, Mievis S, Schoore M, Velu T, Tenenbaum L, Préat V, Bruyns C.
Driessens G, et al. Among authors: nuttin l.
Cancer Immunol Immunother. 2011 Feb;60(2):273-81. doi: 10.1007/s00262-010-0941-y. Epub 2010 Nov 13.
Cancer Immunol Immunother. 2011.
PMID: 21076828
Free PMC article.
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Therapeutic efficacy of antitumor dendritic cell vaccinations correlates with persistent Th1 responses, high intratumor CD8+ T cell recruitment and low relative regulatory T cell infiltration.
Driessens G, Gordower L, Nuttin L, Stordeur P, Blocklet D, Egrise D, Velu T, Bruyns C.
Driessens G, et al. Among authors: nuttin l.
Cancer Immunol Immunother. 2008 Dec;57(12):1745-56. doi: 10.1007/s00262-008-0500-y. Epub 2008 Mar 28.
Cancer Immunol Immunother. 2008.
PMID: 18369621
Free PMC article.
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