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Isolated glucocorticoid deficiency: Genetic causes and animal models.
Maharaj A, Maudhoo A, Chan LF, Novoselova T, Prasad R, Metherell LA, Guasti L. Maharaj A, et al. Among authors: novoselova t. J Steroid Biochem Mol Biol. 2019 May;189:73-80. doi: 10.1016/j.jsbmb.2019.02.012. Epub 2019 Feb 25. J Steroid Biochem Mol Biol. 2019. PMID: 30817990 Review.
Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity.
Asai M, Ramachandrappa S, Joachim M, Shen Y, Zhang R, Nuthalapati N, Ramanathan V, Strochlic DE, Ferket P, Linhart K, Ho C, Novoselova TV, Garg S, Ridderstråle M, Marcus C, Hirschhorn JN, Keogh JM, O'Rahilly S, Chan LF, Clark AJ, Farooqi IS, Majzoub JA. Asai M, et al. Science. 2013 Jul 19;341(6143):275-8. doi: 10.1126/science.1233000. Science. 2013. PMID: 23869016 Free PMC article.
Loss of Mrap2 is associated with Sim1 deficiency and increased circulating cholesterol.
Novoselova TV, Larder R, Rimmington D, Lelliott C, Wynn EH, Gorrigan RJ, Tate PH, Guasti L; Sanger Mouse Genetics Project; O'Rahilly S, Clark AJ, Logan DW, Coll AP, Chan LF. Novoselova TV, et al. J Endocrinol. 2016 Jul;230(1):13-26. doi: 10.1530/JOE-16-0057. Epub 2016 Apr 22. J Endocrinol. 2016. PMID: 27106110 Free PMC article.
MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation.
Novoselova TV, Hussain M, King PJ, Guasti L, Metherell LA, Charalambous M, Clark AJL, Chan LF. Novoselova TV, et al. FASEB J. 2018 Jun 7;32(11):fj201701274RR. doi: 10.1096/fj.201701274RR. Online ahead of print. FASEB J. 2018. PMID: 29879378 Free PMC article.
This is the first mouse model of isolated GC deficiency and reveals the role of MRAP in adrenal progenitor cell regulation and cortex zonation.-Novoselova, T. V., Hussain, M., King, P. J., Guasti, L., Metherell, L. ...
This is the first mouse model of isolated GC deficiency and reveals the role of MRAP in adrenal progenitor cell regulation and cortex zonati …
92 results