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Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells.
Halby L, Menon Y, Rilova E, Pechalrieu D, Masson V, Faux C, Bouhlel MA, David-Cordonnier MH, Novosad N, Aussagues Y, Samson A, Lacroix L, Ausseil F, Fleury L, Guianvarc'h D, Ferroud C, Arimondo PB. Halby L, et al. Among authors: novosad n. J Med Chem. 2017 Jun 8;60(11):4665-4679. doi: 10.1021/acs.jmedchem.7b00176. Epub 2017 May 23. J Med Chem. 2017. PMID: 28463515
Design and synthesis of new non nucleoside inhibitors of DNMT3A.
Erdmann A, Menon Y, Gros C, Molinier N, Novosad N, Samson A, Gregoire JM, Long C, Ausseil F, Halby L, Arimondo PB. Erdmann A, et al. Among authors: novosad n. Bioorg Med Chem. 2015 Sep 1;23(17):5946-53. doi: 10.1016/j.bmc.2015.06.066. Epub 2015 Jul 10. Bioorg Med Chem. 2015. PMID: 26220519
Design, synthesis and biological evaluation of 4-amino-N- (4-aminophenyl)benzamide analogues of quinoline-based SGI-1027 as inhibitors of DNA methylation.
Rilova E, Erdmann A, Gros C, Masson V, Aussagues Y, Poughon-Cassabois V, Rajavelu A, Jeltsch A, Menon Y, Novosad N, Gregoire JM, Vispé S, Schambel P, Ausseil F, Sautel F, Arimondo PB, Cantagrel F. Rilova E, et al. Among authors: novosad n. ChemMedChem. 2014 Mar;9(3):590-601. doi: 10.1002/cmdc.201300420. ChemMedChem. 2014. PMID: 24678024 Free PMC article.
Consequences of combining siRNA-mediated DNA methyltransferase 1 depletion with 5-aza-2'-deoxycytidine in human leukemic KG1 cells.
Vispé S, Deroide A, Davoine E, Desjobert C, Lestienne F, Fournier L, Novosad N, Bréand S, Besse J, Busato F, Tost J, De Vries L, Cussac D, Riond J, Arimondo PB. Vispé S, et al. Among authors: novosad n. Oncotarget. 2015 Jun 20;6(17):15265-82. doi: 10.18632/oncotarget.3317. Oncotarget. 2015. PMID: 25948775 Free PMC article.