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Page 1
Inhibition of Histone Demethylases LSD1 and UTX Regulates ERα Signaling in Breast Cancer.
Benedetti R, Dell'Aversana C, De Marchi T, Rotili D, Liu NQ, Novakovic B, Boccella S, Di Maro S, Cosconati S, Baldi A, Niméus E, Schultz J, Höglund U, Maione S, Papulino C, Chianese U, Iovino F, Federico A, Mai A, Stunnenberg HG, Nebbioso A, Altucci L. Benedetti R, et al. Among authors: novakovic b. Cancers (Basel). 2019 Dec 16;11(12):2027. doi: 10.3390/cancers11122027. Cancers (Basel). 2019. PMID: 31888209 Free PMC article.
β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance.
Novakovic B, Habibi E, Wang SY, Arts RJW, Davar R, Megchelenbrink W, Kim B, Kuznetsova T, Kox M, Zwaag J, Matarese F, van Heeringen SJ, Janssen-Megens EM, Sharifi N, Wang C, Keramati F, Schoonenberg V, Flicek P, Clarke L, Pickkers P, Heath S, Gut I, Netea MG, Martens JHA, Logie C, Stunnenberg HG. Novakovic B, et al. Cell. 2016 Nov 17;167(5):1354-1368.e14. doi: 10.1016/j.cell.2016.09.034. Cell. 2016. PMID: 27863248 Free PMC article.
Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity.
Arts RJ, Novakovic B, Ter Horst R, Carvalho A, Bekkering S, Lachmandas E, Rodrigues F, Silvestre R, Cheng SC, Wang SY, Habibi E, Gonçalves LG, Mesquita I, Cunha C, van Laarhoven A, van de Veerdonk FL, Williams DL, van der Meer JW, Logie C, O'Neill LA, Dinarello CA, Riksen NP, van Crevel R, Clish C, Notebaart RA, Joosten LA, Stunnenberg HG, Xavier RJ, Netea MG. Arts RJ, et al. Among authors: novakovic b. Cell Metab. 2016 Dec 13;24(6):807-819. doi: 10.1016/j.cmet.2016.10.008. Epub 2016 Nov 17. Cell Metab. 2016. PMID: 27866838 Free PMC article.
Uric acid priming in human monocytes is driven by the AKT-PRAS40 autophagy pathway.
Crişan TO, Cleophas MCP, Novakovic B, Erler K, van de Veerdonk FL, Stunnenberg HG, Netea MG, Dinarello CA, Joosten LAB. Crişan TO, et al. Among authors: novakovic b. Proc Natl Acad Sci U S A. 2017 May 23;114(21):5485-5490. doi: 10.1073/pnas.1620910114. Epub 2017 May 8. Proc Natl Acad Sci U S A. 2017. PMID: 28484006 Free PMC article.
Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein.
Keating ST, Groh L, Thiem K, Bekkering S, Li Y, Matzaraki V, van der Heijden CDCC, van Puffelen JH, Lachmandas E, Jansen T, Oosting M, de Bree LCJ, Koeken VACM, Moorlag SJCFM, Mourits VP, van Diepen J, Strienstra R, Novakovic B, Stunnenberg HG, van Crevel R, Joosten LAB, Netea MG, Riksen NP. Keating ST, et al. Among authors: novakovic b. J Mol Med (Berl). 2020 Jun;98(6):819-831. doi: 10.1007/s00109-020-01915-w. Epub 2020 Apr 30. J Mol Med (Berl). 2020. PMID: 32350546 Free PMC article.
Correction to: Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein.
Keating ST, Groh L, Thiem K, Bekkering S, Li Y, Matzaraki V, van der Heijden CDCC, van Puffelen JH, Lachmandas E, Jansen T, Oosting M, de Bree LCJ, Koeken VACM, Moorlag SJCFM, Mourits VP, van Diepen J, Stienstra R, Novakovic B, Stunnenberg HG, van Crevel R, Joosten LAB, Netea MG, Riksen NP. Keating ST, et al. Among authors: novakovic b. J Mol Med (Berl). 2020 Jul;98(7):1051. doi: 10.1007/s00109-020-01939-2. J Mol Med (Berl). 2020. PMID: 32529344 Free PMC article.
Urate-induced epigenetic modifications in myeloid cells.
Badii M, Gaal OI, Cleophas MC, Klück V, Davar R, Habibi E, Keating ST, Novakovic B, Helsen MM, Dalbeth N, Stamp LK, Macartney-Coxson D, Phipps-Green AJ, Stunnenberg HG, Dinarello CA, Merriman TR, Netea MG, Crişan TO, Joosten LAB. Badii M, et al. Among authors: novakovic b. Arthritis Res Ther. 2021 Jul 28;23(1):202. doi: 10.1186/s13075-021-02580-1. Arthritis Res Ther. 2021. PMID: 34321071 Free PMC article.
Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme.
Jentho E, Ruiz-Moreno C, Novakovic B, Kourtzelis I, Megchelenbrink WL, Martins R, Chavakis T, Soares MP, Kalafati L, Guerra J, Roestel F, Bohm P, Godmann M, Grinenko T, Eugster A, Beretta M, Joosten LAB, Netea MG, Bauer M, Stunnenberg HG, Weis S. Jentho E, et al. Among authors: novakovic b. Proc Natl Acad Sci U S A. 2021 Oct 19;118(42):e2102698118. doi: 10.1073/pnas.2102698118. Proc Natl Acad Sci U S A. 2021. PMID: 34663697 Free PMC article.
175 results