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DDX3X acts as a live-or-die checkpoint in stressed cells by regulating NLRP3 inflammasome.
Samir P, Kesavardhana S, Patmore DM, Gingras S, Malireddi RKS, Karki R, Guy CS, Briard B, Place DE, Bhattacharya A, Sharma BR, Nourse A, King SV, Pitre A, Burton AR, Pelletier S, Gilbertson RJ, Kanneganti TD. Samir P, et al. Among authors: nourse a. Nature. 2019 Sep;573(7775):590-594. doi: 10.1038/s41586-019-1551-2. Epub 2019 Sep 11. Nature. 2019. PMID: 31511697 Free PMC article.
An unexpected protein interaction promotes drug resistance in leukemia.
Pitre A, Ge Y, Lin W, Wang Y, Fukuda Y, Temirov J, Phillips AH, Peters JL, Fan Y, Ma J, Nourse A, Sinha C, Lin H, Kriwacki R, Downing JR, Gruber TA, Centonze VE, Naren AP, Chen T, Schuetz JD. Pitre A, et al. Among authors: nourse a. Nat Commun. 2017 Nov 16;8(1):1547. doi: 10.1038/s41467-017-01678-y. Nat Commun. 2017. PMID: 29146910 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35567475
BID-induced structural changes in BAK promote apoptosis.
Moldoveanu T, Grace CR, Llambi F, Nourse A, Fitzgerald P, Gehring K, Kriwacki RW, Green DR. Moldoveanu T, et al. Among authors: nourse a. Nat Struct Mol Biol. 2013 May;20(5):589-97. doi: 10.1038/nsmb.2563. Epub 2013 Apr 21. Nat Struct Mol Biol. 2013. PMID: 23604079 Free PMC article.
Mechanism for the activation of the anaplastic lymphoma kinase receptor.
Reshetnyak AV, Rossi P, Myasnikov AG, Sowaileh M, Mohanty J, Nourse A, Miller DJ, Lax I, Schlessinger J, Kalodimos CG. Reshetnyak AV, et al. Among authors: nourse a. Nature. 2021 Dec;600(7887):153-157. doi: 10.1038/s41586-021-04140-8. Epub 2021 Nov 24. Nature. 2021. PMID: 34819673 Free PMC article.
Direct Activation of Human MLKL by a Select Repertoire of Inositol Phosphate Metabolites.
McNamara DE, Dovey CM, Hale AT, Quarato G, Grace CR, Guibao CD, Diep J, Nourse A, Cai CR, Wu H, Kalathur RC, Green DR, York JD, Carette JE, Moldoveanu T. McNamara DE, et al. Among authors: nourse a. Cell Chem Biol. 2019 Jun 20;26(6):863-877.e7. doi: 10.1016/j.chembiol.2019.03.010. Epub 2019 Apr 25. Cell Chem Biol. 2019. PMID: 31031142 Free PMC article.
53 results