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Structural enzymology using X-ray free electron lasers.
Kupitz C, Olmos JL Jr, Holl M, Tremblay L, Pande K, Pandey S, Oberthür D, Hunter M, Liang M, Aquila A, Tenboer J, Calvey G, Katz A, Chen Y, Wiedorn MO, Knoska J, Meents A, Majriani V, Norwood T, Poudyal I, Grant T, Miller MD, Xu W, Tolstikova A, Morgan A, Metz M, Martin-Garcia JM, Zook JD, Roy-Chowdhury S, Coe J, Nagaratnam N, Meza D, Fromme R, Basu S, Frank M, White T, Barty A, Bajt S, Yefanov O, Chapman HN, Zatsepin N, Nelson G, Weierstall U, Spence J, Schwander P, Pollack L, Fromme P, Ourmazd A, Phillips GN Jr, Schmidt M. Kupitz C, et al. Among authors: norwood t. Struct Dyn. 2016 Dec 15;4(4):044003. doi: 10.1063/1.4972069. eCollection 2017 Jul. Struct Dyn. 2016. PMID: 28083542 Free PMC article.
Enzyme intermediates captured "on the fly" by mix-and-inject serial crystallography.
Olmos JL Jr, Pandey S, Martin-Garcia JM, Calvey G, Katz A, Knoska J, Kupitz C, Hunter MS, Liang M, Oberthuer D, Yefanov O, Wiedorn M, Heyman M, Holl M, Pande K, Barty A, Miller MD, Stern S, Roy-Chowdhury S, Coe J, Nagaratnam N, Zook J, Verburgt J, Norwood T, Poudyal I, Xu D, Koglin J, Seaberg MH, Zhao Y, Bajt S, Grant T, Mariani V, Nelson G, Subramanian G, Bae E, Fromme R, Fung R, Schwander P, Frank M, White TA, Weierstall U, Zatsepin N, Spence J, Fromme P, Chapman HN, Pollack L, Tremblay L, Ourmazd A, Phillips GN Jr, Schmidt M. Olmos JL Jr, et al. Among authors: norwood t. BMC Biol. 2018 May 31;16(1):59. doi: 10.1186/s12915-018-0524-5. BMC Biol. 2018. PMID: 29848358 Free PMC article.
Structural basis for light control of cell development revealed by crystal structures of a myxobacterial phytochrome.
Woitowich NC, Halavaty AS, Waltz P, Kupitz C, Valera J, Tracy G, Gallagher KD, Claesson E, Nakane T, Pandey S, Nelson G, Tanaka R, Nango E, Mizohata E, Owada S, Tono K, Joti Y, Nugent AC, Patel H, Mapara A, Hopkins J, Duong P, Bizhga D, Kovaleva SE, St Peter R, Hernandez CN, Ozarowski WB, Roy-Chowdhuri S, Yang JH, Edlund P, Takala H, Ihalainen J, Brayshaw J, Norwood T, Poudyal I, Fromme P, Spence JCH, Moffat K, Westenhoff S, Schmidt M, Stojković EA. Woitowich NC, et al. Among authors: norwood t. IUCrJ. 2018 Aug 29;5(Pt 5):619-634. doi: 10.1107/S2052252518010631. eCollection 2018 Sep 1. IUCrJ. 2018. PMID: 30224965 Free PMC article.
Placental senescence pathophysiology is shared between peripartum cardiomyopathy and preeclampsia in mouse and human.
Roh JD, Castro C, Yu A, Rana S, Shahul S, Gray KJ, Honigberg MC, Ricke-Hoch M, Iwamoto Y, Yeri A, Kitchen R, Guerra JB, Hobson R, Chaudhari V, Chang B, Sarma A, Lerchenmüller C, Al Sayed ZR, Diaz Verdugo C, Xia P, Skarbianskis N, Zeisel A, Bauersachs J, Kirkland JL, Karumanchi SA, Gorcsan J 3rd, Sugahara M, Damp J, Hanley-Yanez K, Ellinor PT, Arany Z, McNamara DM; IPAC Investigators; Hilfiker-Kleiner D, Rosenzweig A. Roh JD, et al. Sci Transl Med. 2024 Apr 17;16(743):eadi0077. doi: 10.1126/scitranslmed.adi0077. Epub 2024 Apr 17. Sci Transl Med. 2024. PMID: 38630848
Hypoxia-induced cystic fibrosis transmembrane conductance regulator dysfunction is a universal mechanism underlying reduced mucociliary transport in sinusitis.
Cho DY, Zhang S, Norwood TG, Skinner D, Hollis TA, Ehrhardt ML, Yang LC, Lim DJ, Grayson JW, Lazrak A, Matalon S, Rowe SM, Woodworth BA. Cho DY, et al. Among authors: norwood tg. Int Forum Allergy Rhinol. 2023 Dec 11. doi: 10.1002/alr.23309. Online ahead of print. Int Forum Allergy Rhinol. 2023. PMID: 38073611
Serum Proteomic Analysis of Peripartum Cardiomyopathy Reveals Distinctive Dysregulation of Inflammatory and Cholesterol Metabolism Pathways.
Lovell JP, Bermea K, Yu J, Rousseau S, Cohen CD, Bhalodia A, Zita MD, Head RD, Blumenthal RS, Alharethi R, Damp J, Boehmer J, Alexis J, McNamara DM, Sharma G, Adamo L; IPAC; IMAC2 Investigators. Lovell JP, et al. JACC Heart Fail. 2023 Sep;11(9):1231-1242. doi: 10.1016/j.jchf.2023.05.031. Epub 2023 Aug 2. JACC Heart Fail. 2023. PMID: 37542511
The value of virtual physical therapy for musculoskeletal care.
Chen F, Siego CV, Jasik CB, Norwood T, Beresford L, Yang Z, Dall TM. Chen F, et al. Among authors: norwood t. Am J Manag Care. 2023 Jun 1;29(6):e169-e175. doi: 10.37765/ajmc.2023.89375. Am J Manag Care. 2023. PMID: 37341981 Free article.
Advances in Sinus Surgery for Nasal Polyps.
Norwood TG, Grayson JW, Woodworth BA. Norwood TG, et al. Am J Rhinol Allergy. 2023 Mar;37(2):162-167. doi: 10.1177/19458924221147783. Am J Rhinol Allergy. 2023. PMID: 36848271 Review.
140 results