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Discovery and development of 2-aminobenzimidazoles as potent antimalarials.
Devine SM, Challis MP, Kigotho JK, Siddiqui G, De Paoli A, MacRaild CA, Avery VM, Creek DJ, Norton RS, Scammells PJ. Devine SM, et al. Among authors: norton rs. Eur J Med Chem. 2021 Oct 5;221:113518. doi: 10.1016/j.ejmech.2021.113518. Epub 2021 May 13. Eur J Med Chem. 2021. PMID: 34058708
Interaction between Plasmodium falciparum apical membrane antigen 1 and the rhoptry neck protein complex defines a key step in the erythrocyte invasion process of malaria parasites.
Richard D, MacRaild CA, Riglar DT, Chan JA, Foley M, Baum J, Ralph SA, Norton RS, Cowman AF. Richard D, et al. Among authors: norton rs. J Biol Chem. 2010 May 7;285(19):14815-22. doi: 10.1074/jbc.M109.080770. Epub 2010 Mar 12. J Biol Chem. 2010. PMID: 20228060 Free PMC article.
Apical membrane antigen 1 as an anti-malarial drug target.
Macraild CA, Anders RF, Foley M, Norton RS. Macraild CA, et al. Among authors: norton rs. Curr Top Med Chem. 2011;11(16):2039-47. doi: 10.2174/156802611796575885. Curr Top Med Chem. 2011. PMID: 21619512 Review.
Lactam-stabilized helical analogues of the analgesic μ-conotoxin KIIIA.
Khoo KK, Wilson MJ, Smith BJ, Zhang MM, Gulyas J, Yoshikami D, Rivier JE, Bulaj G, Norton RS. Khoo KK, et al. Among authors: norton rs. J Med Chem. 2011 Nov 10;54(21):7558-66. doi: 10.1021/jm200839a. Epub 2011 Oct 12. J Med Chem. 2011. PMID: 21962108 Free PMC article.
Lipid interactions of the malaria antigen merozoite surface protein 2.
MacRaild CA, Pedersen MØ, Anders RF, Norton RS. MacRaild CA, et al. Among authors: norton rs. Biochim Biophys Acta. 2012 Nov;1818(11):2572-8. doi: 10.1016/j.bbamem.2012.06.015. Epub 2012 Jun 27. Biochim Biophys Acta. 2012. PMID: 22749949 Free article.
366 results