Noll B - Search Results

1

Discovery and pharmacological characterization of a novel series of highly selective inhibitors of cyclin-dependent kinases 4 and 6 as anticancer agents.

Tadesse S, Bantie L, Tomusange K, Yu M, Islam S, Bykovska N, Noll B, Zhu G, Li P, Lam F, Kumarasiri M, Milne R, Wang S. Tadesse S, et al. Among authors: noll b. Br J Pharmacol. 2018 Jun;175(12):2399-2413. doi: 10.1111/bph.13974. Epub 2018 May 8. Br J Pharmacol. 2018. PMID: 28800675 Free PMC article.

2

Discovery of (E)-3-((styrylsulfonyl)methyl)pyridine and (E)-2-((styrylsulfonyl)methyl)pyridine derivatives as anticancer agents: synthesis, structure-activity relationships, and biological activities.

Lu T, Goh AW, Yu M, Adams J, Lam F, Teo T, Li P, Noll B, Zhong L, Diab S, Chahrour O, Hu A, Abbas AY, Liu X, Huang S, Sumby CJ, Milne R, Midgley C, Wang S. Lu T, et al. Among authors: noll b. J Med Chem. 2014 Mar 27;57(6):2275-91. doi: 10.1021/jm4019614. Epub 2014 Mar 10. J Med Chem. 2014. PMID: 24471873

3

A novel compound which sensitizes BRAF wild-type melanoma cells to vemurafenib in a TRIM16-dependent manner.

Sutton SK, Carter DR, Kim P, Tan O, Arndt GM, Zhang XD, Baell J, Noll BD, Wang S, Kumar N, McArthur GA, Cheung BB, Marshall GM. Sutton SK, et al. Among authors: noll bd. Oncotarget. 2016 Aug 9;7(32):52166-52178. doi: 10.18632/oncotarget.10700. Oncotarget. 2016. PMID: 27447557 Free PMC article.

4

Highly Potent, Selective, and Orally Bioavailable 4-Thiazol-N-(pyridin-2-yl)pyrimidin-2-amine Cyclin-Dependent Kinases 4 and 6 Inhibitors as Anticancer Drug Candidates: Design, Synthesis, and Evaluation.

Tadesse S, Yu M, Mekonnen LB, Lam F, Islam S, Tomusange K, Rahaman MH, Noll B, Basnet SK, Teo T, Albrecht H, Milne R, Wang S. Tadesse S, et al. Among authors: noll b. J Med Chem. 2017 Mar 9;60(5):1892-1915. doi: 10.1021/acs.jmedchem.6b01670. Epub 2017 Feb 16. J Med Chem. 2017. PMID: 28156111 Free article.

5

Discovery and pharmacological evaluation of a novel series of adamantyl cyanoguanidines as P2X₇ receptor antagonists.

O'Brien-Brown J, Jackson A, Reekie TA, Barron ML, Werry EL, Schiavini P, McDonnell M, Munoz L, Wilkinson S, Noll B, Wang S, Kassiou M. O'Brien-Brown J, et al. Among authors: noll b. Eur J Med Chem. 2017 Apr 21;130:433-439. doi: 10.1016/j.ejmech.2017.02.060. Epub 2017 Mar 2. Eur J Med Chem. 2017. PMID: 28279849

6

Dual Inhibition of Mnk2 and FLT3 for potential treatment of acute myeloid leukaemia.

Diab S, Abdelaziz AM, Li P, Teo T, Basnet SKC, Noll B, Rahaman MH, Lu J, Hou J, Yu M, Le BT, Albrecht H, Milne RW, Wang S. Diab S, et al. Among authors: noll b. Eur J Med Chem. 2017 Oct 20;139:762-772. doi: 10.1016/j.ejmech.2017.08.006. Epub 2017 Aug 3. Eur J Med Chem. 2017. PMID: 28863357

7

CDKI-73: an orally bioavailable and highly efficacious CDK9 inhibitor against acute myeloid leukemia.

Rahaman MH, Yu Y, Zhong L, Adams J, Lam F, Li P, Noll B, Milne R, Peng J, Wang S. Rahaman MH, et al. Among authors: noll b. Invest New Drugs. 2019 Aug;37(4):625-635. doi: 10.1007/s10637-018-0661-2. Epub 2018 Sep 8. Invest New Drugs. 2019. PMID: 30194564

8

Discovery of N-Phenyl-4-(1H-pyrrol-3-yl)pyrimidin-2-amine Derivatives as Potent Mnk2 Inhibitors: Design, Synthesis, SAR Analysis, and Evaluation of in vitro Anti-leukaemic Activity.

Abdelaziz AM, Diab S, Islam S, Basnet SKC, Noll B, Li P, Mekonnen LB, Lu J, Albrecht H, Milne RW, Gerber C, Yu M, Wang S. Abdelaziz AM, et al. Among authors: noll b. Med Chem. 2019;15(6):602-623. doi: 10.2174/1573406415666181219111511. Med Chem. 2019. PMID: 30569866

9

Relationship between allograft cyclosporin concentrations and P-glycoprotein expression in the 1st month following renal transplantation.

Sallustio BC, Noll BD, Coller JK, Tuke J, Russ G, Somogyi AA. Sallustio BC, et al. Br J Clin Pharmacol. 2019 May;85(5):1015-1020. doi: 10.1111/bcp.13880. Epub 2019 Mar 6. Br J Clin Pharmacol. 2019. PMID: 30690767 Free PMC article.

10

Sulfonamide-Based Inhibitors of Biotin Protein Ligase as New Antibiotic Leads.

Lee KJ, Tieu W, Blanco-Rodriguez B, Paparella AS, Yu J, Hayes A, Feng J, Marshall AC, Noll B, Milne R, Cini D, Wilce MCJ, Booker GW, Bruning JB, Polyak SW, Abell AD. Lee KJ, et al. Among authors: noll b. ACS Chem Biol. 2019 Sep 20;14(9):1990-1997. doi: 10.1021/acschembio.9b00463. Epub 2019 Aug 21. ACS Chem Biol. 2019. PMID: 31407891

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