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Page 1
Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools.
De Groot AS, Moise L, Terry F, Gutierrez AH, Hindocha P, Richard G, Hoft DF, Ross TM, Noe AR, Takahashi Y, Kotraiah V, Silk SE, Nielsen CM, Minassian AM, Ashfield R, Ardito M, Draper SJ, Martin WD. De Groot AS, et al. Among authors: noe ar. Front Immunol. 2020 Apr 7;11:442. doi: 10.3389/fimmu.2020.00442. eCollection 2020. Front Immunol. 2020. PMID: 32318055 Free PMC article. Review.
Novel Peptide-Based PD1 Immunomodulators Demonstrate Efficacy in Infectious Disease Vaccines and Therapeutics.
Kotraiah V, Phares TW, Browne CD, Pannucci J, Mansour M, Noe AR, Tucker KD, Christen JM, Reed C, MacKay A, Weir GM, Rajagopalan R, Stanford MM, Chung CS, Ayala A, Huang J, Tsuji M, Gutierrez GM. Kotraiah V, et al. Among authors: noe ar. Front Immunol. 2020 Mar 6;11:264. doi: 10.3389/fimmu.2020.00264. eCollection 2020. Front Immunol. 2020. PMID: 32210956 Free PMC article.
A Peptide-Based PD1 Antagonist Enhances T-Cell Priming and Efficacy of a Prophylactic Malaria Vaccine and Promotes Survival in a Lethal Malaria Model.
Phares TW, Kotraiah V, Karunarathne DS, Huang J, Browne CD, Buontempo P, Mansour M, Noe AR, Wykes MN, Pannucci J, Tsuji M, Gutierrez GM. Phares TW, et al. Among authors: noe ar. Front Immunol. 2020 Jul 9;11:1377. doi: 10.3389/fimmu.2020.01377. eCollection 2020. Front Immunol. 2020. PMID: 32733457 Free PMC article.
Bridging Computational Vaccinology and Vaccine Development Through Systematic Identification, Characterization, and Downselection of Conserved and Variable Circumsporozoite Protein CD4 T Cell Epitopes From Diverse Plasmodium falciparum Strains.
Noe AR, Terry FE, Schanen BC, Sassano E, Hindocha P, Phares TW, Moise L, Christen JM, Tucker KD, Kotraiah V, Drake DR 3rd, Martin WD, De Groot AS, Gutierrez GM. Noe AR, et al. Front Immunol. 2021 Jun 8;12:689920. doi: 10.3389/fimmu.2021.689920. eCollection 2021. Front Immunol. 2021. PMID: 34168657 Free PMC article.
Reduced blood-stage malaria growth and immune correlates in humans following RH5 vaccination.
Minassian AM, Silk SE, Barrett JR, Nielsen CM, Miura K, Diouf A, Loos C, Fallon JK, Michell AR, White MT, Edwards NJ, Poulton ID, Mitton CH, Payne RO, Marks M, Maxwell-Scott H, Querol-Rubiera A, Bisnauthsing K, Batra R, Ogrina T, Brendish NJ, Themistocleous Y, Rawlinson TA, Ellis KJ, Quinkert D, Baker M, Lopez Ramon R, Ramos Lopez F, Barfod L, Folegatti PM, Silman D, Datoo M, Taylor IJ, Jin J, Pulido D, Douglas AD, de Jongh WA, Smith R, Berrie E, Noe AR, Diggs CL, Soisson LA, Ashfield R, Faust SN, Goodman AL, Lawrie AM, Nugent FL, Alter G, Long CA, Draper SJ. Minassian AM, et al. Among authors: noe ar. Med. 2021 Jun 11;2(6):701-719.e19. doi: 10.1016/j.medj.2021.03.014. Med. 2021. PMID: 34223402 Free PMC article.
Identification and Immune Assessment of T Cell Epitopes in Five Plasmodium falciparum Blood Stage Antigens to Facilitate Vaccine Candidate Selection and Optimization.
Kotraiah V, Phares TW, Terry FE, Hindocha P, Silk SE, Nielsen CM, Moise L, Tucker KD, Ashfield R, Martin WD, De Groot AS, Draper SJ, Gutierrez GM, Noe AR. Kotraiah V, et al. Among authors: noe ar. Front Immunol. 2021 Jul 7;12:690348. doi: 10.3389/fimmu.2021.690348. eCollection 2021. Front Immunol. 2021. PMID: 34305923 Free PMC article.
RH5.1-CyRPA-Ripr antigen combination vaccine shows little improvement over RH5.1 in a preclinical setting.
Healer J, Thompson JK, Mackwell KL, Browne CD, Seager BA, Ngo A, Lowes KN, Silk SE, Pulido D, King LDW, Christen JM, Noe AR, Kotraiah V, Masendycz PJ, Rajagopalan R, Lucas L, Stanford MM, Soisson L, Diggs C, Miller R, Youll S, Wycherley K, Draper SJ, Cowman AF. Healer J, et al. Among authors: noe ar. Front Cell Infect Microbiol. 2022 Dec 20;12:1049065. doi: 10.3389/fcimb.2022.1049065. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 36605129 Free PMC article.
A full-length Plasmodium falciparum recombinant circumsporozoite protein expressed by Pseudomonas fluorescens platform as a malaria vaccine candidate.
Noe AR, Espinosa D, Li X, Coelho-Dos-Reis JG, Funakoshi R, Giardina S, Jin H, Retallack DM, Haverstock R, Allen JR, Vedvick TS, Fox CB, Reed SG, Ayala R, Roberts B, Winram SB, Sacci J, Tsuji M, Zavala F, Gutierrez GM. Noe AR, et al. PLoS One. 2014 Sep 23;9(9):e107764. doi: 10.1371/journal.pone.0107764. eCollection 2014. PLoS One. 2014. PMID: 25247295 Free PMC article.
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