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miRNA-Mediated Knockdown of ATXN3 Alleviates Molecular Disease Hallmarks in a Mouse Model for Spinocerebellar Ataxia Type 3.
Nobre RJ, Lobo DD, Henriques C, Duarte SP, Lopes SM, Silva AC, Lopes MM, Mariet F, Schwarz LK, Baatje MS, Ferreira V, Vallès A, Pereira de Almeida L, Evers MM, Toonen LJA. Nobre RJ, et al. Nucleic Acid Ther. 2022 Jun;32(3):194-205. doi: 10.1089/nat.2021.0020. Epub 2021 Dec 7. Nucleic Acid Ther. 2022. PMID: 34878314 Free PMC article.
Gene Therapies for Polyglutamine Diseases.
Matos CA, Carmona V, Vijayakumar UG, Lopes S, Albuquerque P, Conceição M, Nobre RJ, Nóbrega C, de Almeida LP. Matos CA, et al. Among authors: nobre rj. Adv Exp Med Biol. 2018;1049:395-438. doi: 10.1007/978-3-319-71779-1_20. Adv Exp Med Biol. 2018. PMID: 29427115 Review.
Repeated Mesenchymal Stromal Cell Treatment Sustainably Alleviates Machado-Joseph Disease.
Oliveira Miranda C, Marcelo A, Silva TP, Barata J, Vasconcelos-Ferreira A, Pereira D, Nóbrega C, Duarte S, Barros I, Alves J, Sereno J, Petrella LI, Castelhano J, Paiva VH, Rodrigues-Santos P, Alves V, Nunes-Correia I, Nobre RJ, Gomes C, Castelo-Branco M, Pereira de Almeida L. Oliveira Miranda C, et al. Among authors: nobre rj. Mol Ther. 2018 Sep 5;26(9):2131-2151. doi: 10.1016/j.ymthe.2018.07.007. Epub 2018 Jul 12. Mol Ther. 2018. PMID: 30087083 Free PMC article.
Protocol for the Characterization of the Cytosine-Adenine-Guanine Tract and Flanking Polymorphisms in Machado-Joseph Disease: Impact on Diagnosis and Development of Gene-Based Therapies.
Lopes SM, Faro R, Lopes MM, Onofre I, Mendonça N, Ribeiro J, Januário C, Nobre RJ, Pereira de Almeida L. Lopes SM, et al. Among authors: nobre rj. J Mol Diagn. 2020 Jun;22(6):782-793. doi: 10.1016/j.jmoldx.2020.03.003. Epub 2020 Mar 20. J Mol Diagn. 2020. PMID: 32205289 Free article.
Trehalose alleviates the phenotype of Machado-Joseph disease mouse models.
Santana MM, Paixão S, Cunha-Santos J, Silva TP, Trevino-Garcia A, Gaspar LS, Nóbrega C, Nobre RJ, Cavadas C, Greif H, Pereira de Almeida L. Santana MM, et al. Among authors: nobre rj. J Transl Med. 2020 Apr 9;18(1):161. doi: 10.1186/s12967-020-02302-2. J Transl Med. 2020. PMID: 32272938 Free PMC article.
28 results