No JH - Search Results

1

Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against Mycobacterium abscessus and Malaria Parasites.

Stampolaki M, Malwal SR, Alvarez-Cabrera N, Gao Z, Moniruzzaman M, Babii SO, Naziris N, Rey-Cibati A, Valladares-Delgado M, Turcu AL, Baek KH, Phan TN, Lee H, Alcaraz M, Watson S, van der Watt M, Coertzen D, Efstathiou N, Chountoulesi M, Shoen CM, Papanastasiou IP, Brea J, Cynamon MH, Birkholtz LM, Kremer L, No JH, Vázquez S, Benaim G, Demetzos C, Zgurskaya HI, Dick T, Oldfield E, Kolocouris AD. Stampolaki M, et al. Among authors: no jh. ACS Infect Dis. 2023 Feb 10;9(2):342-364. doi: 10.1021/acsinfecdis.2c00537. Epub 2023 Jan 27. ACS Infect Dis. 2023. PMID: 36706233 Free PMC article.

2

Bisphosphonate inhibition of a Plasmodium farnesyl diphosphate synthase and a general method for predicting cell-based activity from enzyme data.

Mukkamala D, No JH, Cass LM, Chang TK, Oldfield E. Mukkamala D, et al. Among authors: no jh. J Med Chem. 2008 Dec 25;51(24):7827-33. doi: 10.1021/jm8009074. J Med Chem. 2008. PMID: 19053772 Free PMC article.

3

Inhibition of the Fe(4)S(4)-cluster-containing protein IspH (LytB): electron paramagnetic resonance, metallacycles, and mechanisms.

Wang K, Wang W, No JH, Zhang Y, Zhang Y, Oldfield E. Wang K, et al. Among authors: no jh. J Am Chem Soc. 2010 May 19;132(19):6719-27. doi: 10.1021/ja909664j. J Am Chem Soc. 2010. PMID: 20426416 Free PMC article.

4

Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity.

No JH, de Macedo Dossin F, Zhang Y, Liu YL, Zhu W, Feng X, Yoo JA, Lee E, Wang K, Hui R, Freitas-Junior LH, Oldfield E. No JH, et al. Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4058-63. doi: 10.1073/pnas.1118215109. Epub 2012 Mar 5. Proc Natl Acad Sci U S A. 2012. PMID: 22392982 Free PMC article.

5

Chemo-Immunotherapeutic Anti-Malarials Targeting Isoprenoid Biosynthesis.

Zhang Y, Zhu W, Liu YL, Wang H, Wang K, Li K, No JH, Ayong L, Gulati A, Pang R, Freitas-Junior L, Morita CT, Old-Field E. Zhang Y, et al. Among authors: no jh. ACS Med Chem Lett. 2013 Apr 11;4(4):423-427. doi: 10.1021/ml4000436. ACS Med Chem Lett. 2013. PMID: 23610597 Free PMC article.

6

Multitarget drug discovery for tuberculosis and other infectious diseases.

Li K, Schurig-Briccio LA, Feng X, Upadhyay A, Pujari V, Lechartier B, Fontes FL, Yang H, Rao G, Zhu W, Gulati A, No JH, Cintra G, Bogue S, Liu YL, Molohon K, Orlean P, Mitchell DA, Freitas-Junior L, Ren F, Sun H, Jiang T, Li Y, Guo RT, Cole ST, Gennis RB, Crick DC, Oldfield E. Li K, et al. Among authors: no jh. J Med Chem. 2014 Apr 10;57(7):3126-39. doi: 10.1021/jm500131s. Epub 2014 Apr 1. J Med Chem. 2014. PMID: 24568559 Free PMC article.

7

Oxa, Thia, Heterocycle, and Carborane Analogues of SQ109: Bacterial and Protozoal Cell Growth Inhibitors.

Li K, Wang Y, Yang G, Byun S, Rao G, Shoen C, Yang H, Gulati A, Crick DC, Cynamon M, Huang G, Docampo R, No JH, Oldfield E. Li K, et al. Among authors: no jh. ACS Infect Dis. 2015 May 8;1(5):215-221. doi: 10.1021/acsinfecdis.5b00026. ACS Infect Dis. 2015. PMID: 26258172 Free PMC article.

8

In Vitro and in Vivo Activity of Multitarget Inhibitors against Trypanosoma brucei.

Yang G, Zhu W, Wang Y, Huang G, Byun SY, Choi G, Li K, Huang Z, Docampo R, Oldfield E, No JH. Yang G, et al. Among authors: no jh. ACS Infect Dis. 2015 Aug 14;1(8):388-98. doi: 10.1021/acsinfecdis.5b00068. Epub 2015 Jul 31. ACS Infect Dis. 2015. PMID: 26295062 Free PMC article.

9

In Vitro and In Vivo Investigation of the Inhibition of Trypanosoma brucei Cell Growth by Lipophilic Bisphosphonates.

Yang G, Zhu W, Kim K, Byun SY, Choi G, Wang K, Cha JS, Cho HS, Oldfield E, No JH. Yang G, et al. Among authors: no jh. Antimicrob Agents Chemother. 2015 Dec;59(12):7530-9. doi: 10.1128/AAC.01873-15. Epub 2015 Sep 21. Antimicrob Agents Chemother. 2015. PMID: 26392508 Free PMC article.

10

In Vitro and in Vivo Activity of mTOR Kinase and PI3K Inhibitors Against Leishmania donovani and Trypanosoma brucei.

Phan TN, Baek KH, Lee N, Byun SY, Shum D, No JH. Phan TN, et al. Among authors: no jh. Molecules. 2020 Apr 23;25(8):1980. doi: 10.3390/molecules25081980. Molecules. 2020. PMID: 32340370 Free PMC article.

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