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The mechanism of ceftazidime and cefiderocol hydrolysis by D179Y variants of KPC carbapenemases is similar and involves the formation of a long-lived covalent intermediate.
Antimicrob Agents Chemother. 2024 Mar 6;68(3):e0110823. doi: 10.1128/aac.01108-23. Epub 2024 Jan 23.
Antimicrob Agents Chemother. 2024.
PMID: 38259088
DNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors.
Jimmidi R, Chamakuri S, Lu S, Ucisik MN, Chen PJ, Bohren KM, Moghadasi SA, Versteeg L, Nnabuife C, Li JY, Qin X, Chen YC, Faver JC, Nyshadham P, Sharma KL, Sankaran B, Judge A, Yu Z, Li F, Pollet J, Harris RS, Matzuk MM, Palzkill T, Young DW.
Jimmidi R, et al. Among authors: nnabuife c.
Commun Chem. 2023 Aug 4;6(1):164. doi: 10.1038/s42004-023-00961-y.
Commun Chem. 2023.
PMID: 37542196
Free PMC article.
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Transmissible SARS-CoV-2 variants with resistance to clinical protease inhibitors.
Moghadasi SA, Heilmann E, Khalil AM, Nnabuife C, Kearns FL, Ye C, Moraes SN, Costacurta F, Esler MA, Aihara H, von Laer D, Martinez-Sobrido L, Palzkill T, Amaro RE, Harris RS.
Moghadasi SA, et al. Among authors: nnabuife c.
Sci Adv. 2023 Mar 29;9(13):eade8778. doi: 10.1126/sciadv.ade8778. Epub 2023 Mar 29.
Sci Adv. 2023.
PMID: 36989354
Free PMC article.
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Transmissible SARS-CoV-2 variants with resistance to clinical protease inhibitors.
Moghadasi SA, Heilmann E, Khalil AM, Nnabuife C, Kearns FL, Ye C, Moraes SN, Costacurta F, Esler MA, Aihara H, von Laer D, Martinez-Sobrido L, Palzkill T, Amaro RE, Harris RS.
Moghadasi SA, et al. Among authors: nnabuife c.
bioRxiv [Preprint]. 2022 Dec 26:2022.08.07.503099. doi: 10.1101/2022.08.07.503099.
bioRxiv. 2022.
PMID: 35982678
Free PMC article.
Updated.
Preprint.
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Serum creatinine changes in HIV-seropositive patients receiving tenofovir.
El Sahly HM, Teeter L, Zerai T, Andrade RA, Munoz C, Nnabuife C, Hunter R.
El Sahly HM, et al. Among authors: nnabuife c.
AIDS. 2006 Mar 21;20(5):786-7. doi: 10.1097/01.aids.0000216386.60481.47.
AIDS. 2006.
PMID: 16514316
No abstract available.
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