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Two Theileria parva CD8 T cell antigen genes are more variable in buffalo than cattle parasites, but differ in pattern of sequence diversity.
Pelle R, Graham SP, Njahira MN, Osaso J, Saya RM, Odongo DO, Toye PG, Spooner PR, Musoke AJ, Mwangi DM, Taracha EL, Morrison WI, Weir W, Silva JC, Bishop RP. Pelle R, et al. Among authors: njahira mn. PLoS One. 2011 Apr 29;6(4):e19015. doi: 10.1371/journal.pone.0019015. PLoS One. 2011. PMID: 21559495 Free PMC article.
Genes encoding two Theileria parva antigens recognized by CD8+ T-cells exhibit sequence diversity in South Sudanese cattle populations but the majority of alleles are similar to the Muguga component of the live vaccine cocktail.
Salih DA, Pelle R, Mwacharo JM, Njahira MN, Marcellino WL, Kiara H, Malak AK, El Hussein AR, Bishop R, Skilton RA. Salih DA, et al. Among authors: njahira mn. PLoS One. 2017 Feb 23;12(2):e0171426. doi: 10.1371/journal.pone.0171426. eCollection 2017. PLoS One. 2017. PMID: 28231338 Free PMC article.
Transcriptomics reveal potential vaccine antigens and a drastic increase of upregulated genes during Theileria parva development from arthropod to bovine infective stages.
Tonui T, Corredor-Moreno P, Kanduma E, Njuguna J, Njahira MN, Nyanjom SG, Silva JC, Djikeng A, Pelle R. Tonui T, et al. Among authors: njahira mn. PLoS One. 2018 Oct 10;13(10):e0204047. doi: 10.1371/journal.pone.0204047. eCollection 2018. PLoS One. 2018. PMID: 30303978 Free PMC article.
Theileria parva candidate vaccine antigens recognized by immune bovine cytotoxic T lymphocytes.
Graham SP, Pellé R, Honda Y, Mwangi DM, Tonukari NJ, Yamage M, Glew EJ, de Villiers EP, Shah T, Bishop R, Abuya E, Awino E, Gachanja J, Luyai AE, Mbwika F, Muthiani AM, Ndegwa DM, Njahira M, Nyanjui JK, Onono FO, Osaso J, Saya RM, Wildmann C, Fraser CM, Maudlin I, Gardner MJ, Morzaria SP, Loosmore S, Gilbert SC, Audonnet JC, van der Bruggen P, Nene V, Taracha EL. Graham SP, et al. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3286-91. doi: 10.1073/pnas.0511273103. Epub 2006 Feb 21. Proc Natl Acad Sci U S A. 2006. PMID: 16492763 Free PMC article. Clinical Trial.
Genetic diversity and population structure of Theileria parva in South Sudan.
Salih DA, Mwacharo JM, Pelle R, Njahira MN, Odongo DO, Mbole-Kariuki MN, Marcellino WL, Malak AK, Kiara H, El Hussein ARM, Bishop RP, Skilton RA. Salih DA, et al. Among authors: njahira mn. Ticks Tick Borne Dis. 2018 May;9(4):806-813. doi: 10.1016/j.ttbdis.2018.03.002. Epub 2018 Mar 3. Ticks Tick Borne Dis. 2018. PMID: 29534988
Antigen gene and variable number tandem repeat (VNTR) diversity in Theileria parva parasites from Ankole cattle in south-western Uganda: Evidence for conservation in antigen gene sequences combined with extensive polymorphism at VNTR loci.
Nanteza A, Obara I, Kasaija P, Mwega E, Kabi F, Salih DA, Njahira M, Njuguna J, Odongo D, Bishop RP, Skilton RA, Ahmed J, Clausen PH, Lubega GW. Nanteza A, et al. Transbound Emerg Dis. 2020 Mar;67 Suppl 1:99-107. doi: 10.1111/tbed.13311. Transbound Emerg Dis. 2020. PMID: 32174038
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