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Synthon-based ligand discovery in virtual libraries of over 11 billion compounds.
Sadybekov AA, Sadybekov AV, Liu Y, Iliopoulos-Tsoutsouvas C, Huang XP, Pickett J, Houser B, Patel N, Tran NK, Tong F, Zvonok N, Jain MK, Savych O, Radchenko DS, Nikas SP, Petasis NA, Moroz YS, Roth BL, Makriyannis A, Katritch V. Sadybekov AA, et al. Among authors: nikas sp. Nature. 2022 Jan;601(7893):452-459. doi: 10.1038/s41586-021-04220-9. Epub 2021 Dec 15. Nature. 2022. PMID: 34912117 Free PMC article.
Novel 1',1'-chain substituted Delta(8)-tetrahydrocannabinols.
Papahatjis DP, Nikas SP, Andreou T, Makriyannis A. Papahatjis DP, et al. Among authors: nikas sp. Bioorg Med Chem Lett. 2002 Dec 16;12(24):3583-6. doi: 10.1016/s0960-894x(02)00785-0. Bioorg Med Chem Lett. 2002. PMID: 12443781
CB1 cannabinoid receptor ligands.
Thakur GA, Nikas SP, Makriyannis A. Thakur GA, et al. Among authors: nikas sp. Mini Rev Med Chem. 2005 Jul;5(7):631-40. doi: 10.2174/1389557054368772. Mini Rev Med Chem. 2005. PMID: 16026309 Review.
Methods for the synthesis of cannabinergic ligands.
Thakur GA, Nikas SP, Duclos RI Jr, Makriyannis A. Thakur GA, et al. Among authors: nikas sp. Methods Mol Med. 2006;123:113-48. doi: 10.1385/1-59259-999-0:113. Methods Mol Med. 2006. PMID: 16506405
Cannabinoid receptors as therapeutic targets.
Pavlopoulos S, Thakur GA, Nikas SP, Makriyannis A. Pavlopoulos S, et al. Among authors: nikas sp. Curr Pharm Des. 2006;12(14):1751-69. doi: 10.2174/138161206776873743. Curr Pharm Des. 2006. PMID: 16712486 Review.
Aspirin-triggered metabolites of EFAs.
Makriyannis A, Nikas SP. Makriyannis A, et al. Among authors: nikas sp. Chem Biol. 2011 Oct 28;18(10):1208-9. doi: 10.1016/j.chembiol.2011.10.005. Chem Biol. 2011. PMID: 22035788 Free PMC article.
72 results