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Cancer vulnerabilities unveiled by genomic loss.
Nijhawan D, Zack TI, Ren Y, Strickland MR, Lamothe R, Schumacher SE, Tsherniak A, Besche HC, Rosenbluh J, Shehata S, Cowley GS, Weir BA, Goldberg AL, Mesirov JP, Root DE, Bhatia SN, Beroukhim R, Hahn WC. Nijhawan D, et al. Cell. 2012 Aug 17;150(4):842-54. doi: 10.1016/j.cell.2012.07.023. Cell. 2012. PMID: 22901813 Free PMC article.
Regulating TERT: location, location, location.
Rosenbluh J, Nijhawan D, Hahn WC. Rosenbluh J, et al. Among authors: nijhawan d. Cell Cycle. 2009 Oct 15;8(20):3257. doi: 10.4161/cc.8.20.10037. Epub 2009 Oct 15. Cell Cycle. 2009. PMID: 19823010 No abstract available.
RMRP is a non-coding RNA essential for early murine development.
Rosenbluh J, Nijhawan D, Chen Z, Wong KK, Masutomi K, Hahn WC. Rosenbluh J, et al. Among authors: nijhawan d. PLoS One. 2011;6(10):e26270. doi: 10.1371/journal.pone.0026270. Epub 2011 Oct 19. PLoS One. 2011. PMID: 22039455 Free PMC article.
β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis.
Rosenbluh J, Nijhawan D, Cox AG, Li X, Neal JT, Schafer EJ, Zack TI, Wang X, Tsherniak A, Schinzel AC, Shao DD, Schumacher SE, Weir BA, Vazquez F, Cowley GS, Root DE, Mesirov JP, Beroukhim R, Kuo CJ, Goessling W, Hahn WC. Rosenbluh J, et al. Among authors: nijhawan d. Cell. 2012 Dec 21;151(7):1457-73. doi: 10.1016/j.cell.2012.11.026. Epub 2012 Dec 13. Cell. 2012. PMID: 23245941 Free PMC article.
Inducible mismatch repair streamlines forward genetic approaches to target identification of cytotoxic small molecules.
Nguyen TP, Fang M, Kim J, Wang B, Lin E, Khivansara V, Barrows N, Rivera-Cancel G, Goralski M, Cervantes CL, Xie S, Peterson JM, Povedano JM, Antczak MI, Posner BA, Harvey CJB, Naughton BT, McFadden DG, Ready JM, De Brabander JK, Nijhawan D. Nguyen TP, et al. Among authors: nijhawan d. Cell Chem Biol. 2023 Nov 16;30(11):1453-1467.e8. doi: 10.1016/j.chembiol.2023.07.017. Epub 2023 Aug 21. Cell Chem Biol. 2023. PMID: 37607550
Anticancer benzoxaboroles block pre-mRNA processing by directly inhibiting CPSF3.
Tao Y, Budhipramono A, Huang J, Fang M, Xie S, Kim J, Khivansara V, Dominski Z, Tong L, De Brabander JK, Nijhawan D. Tao Y, et al. Among authors: nijhawan d. Cell Chem Biol. 2024 Jan 18;31(1):139-149.e14. doi: 10.1016/j.chembiol.2023.10.019. Epub 2023 Nov 14. Cell Chem Biol. 2024. PMID: 37967558
Apoptosis in neural development and disease.
Nijhawan D, Honarpour N, Wang X. Nijhawan D, et al. Annu Rev Neurosci. 2000;23:73-87. doi: 10.1146/annurev.neuro.23.1.73. Annu Rev Neurosci. 2000. PMID: 10845059 Review.
36 results