Nieva JL - Search Results

1

Engineering pan-HIV-1 neutralization potency through multispecific antibody avidity.

Rujas E, Cui H, Burnie J, Aschner CB, Zhao T, Insausti S, Muthuraman K, Semesi A, Ophel J, Nieva JL, Seaman MS, Guzzo C, Treanor B, Julien JP. Rujas E, et al. Among authors: nieva jl. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2112887119. doi: 10.1073/pnas.2112887119. Proc Natl Acad Sci U S A. 2022. PMID: 35064083 Free PMC article.

2

Structural details of HIV-1 recognition by the broadly neutralizing monoclonal antibody 2F5: epitope conformation, antigen-recognition loop mobility, and anion-binding site.

Julien JP, Bryson S, Nieva JL, Pai EF. Julien JP, et al. Among authors: nieva jl. J Mol Biol. 2008 Dec 12;384(2):377-92. doi: 10.1016/j.jmb.2008.09.024. Epub 2008 Sep 18. J Mol Biol. 2008. PMID: 18824005

3

Structural constraints imposed by the conserved fusion peptide on the HIV-1 gp41 epitope recognized by the broadly neutralizing antibody 2F5.

de la Arada I, Julien JP, de la Torre BG, Huarte N, Andreu D, Pai EF, Arrondo JL, Nieva JL. de la Arada I, et al. Among authors: nieva jl. J Phys Chem B. 2009 Oct 15;113(41):13626-37. doi: 10.1021/jp905965h. J Phys Chem B. 2009. PMID: 19754136

4

Ablation of the complementarity-determining region H3 apex of the anti-HIV-1 broadly neutralizing antibody 2F5 abrogates neutralizing capacity without affecting core epitope binding.

Julien JP, Huarte N, Maeso R, Taneva SG, Cunningham A, Nieva JL, Pai EF. Julien JP, et al. Among authors: nieva jl. J Virol. 2010 May;84(9):4136-47. doi: 10.1128/JVI.02357-09. Epub 2010 Feb 10. J Virol. 2010. PMID: 20147404 Free PMC article.

5

Interaction of anti-HIV type 1 antibody 2F5 with phospholipid bilayers and its relevance for the mechanism of virus neutralization.

Maeso R, Huarte N, Julien JP, Kunert R, Pai EF, Nieva JL. Maeso R, et al. Among authors: nieva jl. AIDS Res Hum Retroviruses. 2011 Aug;27(8):863-76. doi: 10.1089/AID.2010.0265. Epub 2011 Jan 15. AIDS Res Hum Retroviruses. 2011. PMID: 21142698

6

Recognition of membrane-bound fusion-peptide/MPER complexes by the HIV-1 neutralizing 2F5 antibody: implications for anti-2F5 immunogenicity.

Huarte N, Araujo A, Arranz R, Lorizate M, Quendler H, Kunert R, Valpuesta JM, Nieva JL. Huarte N, et al. Among authors: nieva jl. PLoS One. 2012;7(12):e52740. doi: 10.1371/journal.pone.0052740. Epub 2012 Dec 21. PLoS One. 2012. PMID: 23285173 Free PMC article.

7

Structure and immunogenicity of a peptide vaccine, including the complete HIV-1 gp41 2F5 epitope: implications for antibody recognition mechanism and immunogen design.

Serrano S, Araujo A, Apellániz B, Bryson S, Carravilla P, de la Arada I, Huarte N, Rujas E, Pai EF, Arrondo JLR, Domene C, Jiménez MA, Nieva JL. Serrano S, et al. Among authors: nieva jl. J Biol Chem. 2014 Mar 7;289(10):6565-6580. doi: 10.1074/jbc.M113.527747. Epub 2014 Jan 15. J Biol Chem. 2014. PMID: 24429284 Free PMC article.

8

Cholesterol-dependent membrane fusion induced by the gp41 membrane-proximal external region-transmembrane domain connection suggests a mechanism for broad HIV-1 neutralization.

Apellániz B, Rujas E, Carravilla P, Requejo-Isidro J, Huarte N, Domene C, Nieva JL. Apellániz B, et al. Among authors: nieva jl. J Virol. 2014 Nov;88(22):13367-77. doi: 10.1128/JVI.02151-14. Epub 2014 Sep 10. J Virol. 2014. PMID: 25210180 Free PMC article.

9

The Atomic Structure of the HIV-1 gp41 Transmembrane Domain and Its Connection to the Immunogenic Membrane-proximal External Region.

Apellániz B, Rujas E, Serrano S, Morante K, Tsumoto K, Caaveiro JM, Jiménez MÁ, Nieva JL. Apellániz B, et al. Among authors: nieva jl. J Biol Chem. 2015 May 22;290(21):12999-3015. doi: 10.1074/jbc.M115.644351. Epub 2015 Mar 18. J Biol Chem. 2015. PMID: 25787074 Free PMC article.

10

Structural and Thermodynamic Basis of Epitope Binding by Neutralizing and Nonneutralizing Forms of the Anti-HIV-1 Antibody 4E10.

Rujas E, Gulzar N, Morante K, Tsumoto K, Scott JK, Nieva JL, Caaveiro JM. Rujas E, et al. Among authors: nieva jl. J Virol. 2015 Dec;89(23):11975-89. doi: 10.1128/JVI.01793-15. Epub 2015 Sep 16. J Virol. 2015. PMID: 26378169 Free PMC article.

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