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Trimethylangelicin reduces IL-8 transcription and potentiates CFTR function.
Tamanini A, Borgatti M, Finotti A, Piccagli L, Bezzerri V, Favia M, Guerra L, Lampronti I, Bianchi N, Dall'Acqua F, Vedaldi D, Salvador A, Fabbri E, Mancini I, Nicolis E, Casavola V, Cabrini G, Gambari R. Tamanini A, et al. Among authors: nicolis e. Am J Physiol Lung Cell Mol Physiol. 2011 Mar;300(3):L380-90. doi: 10.1152/ajplung.00129.2010. Epub 2010 Dec 10. Am J Physiol Lung Cell Mol Physiol. 2011. PMID: 21148790 Free article.
We previously found that 5-methoxypsoralen reduces Pseudomonas aeruginosa-dependent IL-8 transcription in bronchial epithelial cell lines, with an IC(50) of 10 muM (Nicolis E, Lampronti I, Dechecchi MC, Borgatti M, Tamanini A, Bezzerri V, Bianchi N, Mazzon M, Mancin …
We previously found that 5-methoxypsoralen reduces Pseudomonas aeruginosa-dependent IL-8 transcription in bronchial epithelial cell lines, w …
Anti-inflammatory effect of miglustat in bronchial epithelial cells.
Dechecchi MC, Nicolis E, Norez C, Bezzerri V, Borgatti M, Mancini I, Rizzotti P, Ribeiro CM, Gambari R, Becq F, Cabrini G. Dechecchi MC, et al. Among authors: nicolis e. J Cyst Fibros. 2008 Nov;7(6):555-65. doi: 10.1016/j.jcf.2008.06.002. Epub 2008 Sep 23. J Cyst Fibros. 2008. PMID: 18815075 Free article.
Am J Physiol Lung Cell Mol Physiol 2007; 292:L383-L395.] recently demonstrated that the inhibition of function of w/t CFTR produces an inflammatory profile that resembles that observed in CF patients, whereas we found that correction of F508del-CFTR function with MPB-07 down-modu …
Am J Physiol Lung Cell Mol Physiol 2007; 292:L383-L395.] recently demonstrated that the inhibition of function of w/t CFTR produces an infla …
Targeting transcription factor activity as a strategy to inhibit pro-inflammatory genes involved in cystic fibrosis: decoy oligonucleotides and low-molecular weight compounds.
Cabrini G, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Tamanini A, Lampronti I, Piccagli L, Bianchi N, Borgatti M, Gambari R. Cabrini G, et al. Among authors: nicolis e. Curr Med Chem. 2010;17(35):4392-404. doi: 10.2174/092986710793361243. Curr Med Chem. 2010. PMID: 20939807 Review.
Effects of decoy molecules targeting NF-kappaB transcription factors in Cystic fibrosis IB3-1 cells: recruitment of NF-kappaB to the IL-8 gene promoter and transcription of the IL-8 gene.
Finotti A, Borgatti M, Bezzerri V, Nicolis E, Lampronti I, Dechecchi M, Mancini I, Cabrini G, Saviano M, Avitabile C, Romanelli A, Gambari R. Finotti A, et al. Among authors: nicolis e. Artif DNA PNA XNA. 2012 Apr-Jun;3(2):97-296. doi: 10.4161/adna.21061. Epub 2012 Apr 1. Artif DNA PNA XNA. 2012. PMID: 22772035 Free PMC article.
Induction of IL-6 gene expression in a CF bronchial epithelial cell line by Pseudomonas aeruginosa is dependent on transcription factors belonging to the Sp1 superfamily.
Borgatti M, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Lampronti I, Rizzotti P, Cabrini G, Gambari R. Borgatti M, et al. Among authors: nicolis e. Biochem Biophys Res Commun. 2007 Jun 15;357(4):977-83. doi: 10.1016/j.bbrc.2007.04.081. Epub 2007 Apr 20. Biochem Biophys Res Commun. 2007. PMID: 17466942
83 results