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Colchicine exerts anti-atherosclerotic and -plaque-stabilizing effects targeting foam cell formation.
Schwarz N, Fernando S, Chen YC, Salagaras T, Rao SR, Liyanage S, Williamson AE, Toledo-Flores D, Dimasi C, Sargeant TJ, Manavis J, Eddy E, Kanellakis P, Thompson PL, Tan JTM, Snel MF, Bursill CA, Nicholls SJ, Peter K, Psaltis PJ. Schwarz N, et al. Among authors: nicholls sj. FASEB J. 2023 Apr;37(4):e22846. doi: 10.1096/fj.202201469R. FASEB J. 2023. PMID: 36856983
Coronary Atheroma Regression With Evolocumab in Stable and Unstable Coronary Syndromes.
Nicholls SJ, Kataoka Y, Nissen SE, Prati F, Windecker S, Puri R, Hucko T, Aradi D, Herrman JR, Hermanides RS, Wang B, Wang H, Butters J, Giovanni GD, Jones S, Pompili G, Wolski K, Psaltis PJ. Nicholls SJ, et al. JACC Cardiovasc Imaging. 2023 Jan;16(1):130-132. doi: 10.1016/j.jcmg.2022.07.020. Epub 2022 Nov 16. JACC Cardiovasc Imaging. 2023. PMID: 36599559 Free article. No abstract available.
The effect of continuous glucose monitoring-guided glycemic control on progression of coronary atherosclerosis in type 2 diabetic patients with coronary artery disease: The OPTIMAL randomized clinical trial.
Kataoka Y, Kitahara S, Funabashi S, Makino H, Matsubara M, Matsuo M, Omura-Ohata Y, Koezuka R, Tochiya M, Tamanaha T, Tomita T, Honda-Kohmo K, Noguchi M, Maruki M, Kanai E, Murai K, Iwai T, Sawada K, Matama H, Honda S, Fujino M, Yoneda S, Takagi K, Otsuka F, Asaumi Y, Hosoda K, Nicholls SJ, Yasuda S, Noguchi T. Kataoka Y, et al. Among authors: nicholls sj. J Diabetes Complications. 2023 Oct;37(10):108592. doi: 10.1016/j.jdiacomp.2023.108592. Epub 2023 Aug 23. J Diabetes Complications. 2023. PMID: 37741088 Free article. Clinical Trial.
Calcified plaque harboring lipidic materials associates with no-reflow phenomenon after PCI in stable CAD.
Hosoda H, Kataoka Y, Nicholls SJ, Puri R, Murai K, Kitahara S, Mitsui K, Sugane H, Sawada K, Iwai T, Matama H, Honda S, Takagi K, Fujino M, Yoneda S, Otsuka F, Takamisawa I, Nishihira K, Asaumi Y, Kawai K, Noguchi T. Hosoda H, et al. Among authors: nicholls sj. Int J Cardiovasc Imaging. 2023 Oct;39(10):1927-1941. doi: 10.1007/s10554-023-02905-y. Epub 2023 Jun 28. Int J Cardiovasc Imaging. 2023. PMID: 37378706 Free PMC article.
Characterization of plaque phenotypes exhibiting an elevated pericoronary adipose tissue attenuation: insights from the REASSURE-NIRS registry.
Kitahara S, Kataoka Y, Miura H, Nishii T, Nishimura K, Murai K, Iwai T, Matama H, Honda S, Fujino M, Yoneda S, Takagi K, Otsuka F, Asaumi Y, Fujino Y, Tsujita K, Puri R, Nicholls SJ, Noguchi T. Kitahara S, et al. Among authors: nicholls sj. Int J Cardiovasc Imaging. 2023 Oct;39(10):1943-1952. doi: 10.1007/s10554-023-02907-w. Epub 2023 Jun 29. Int J Cardiovasc Imaging. 2023. PMID: 37380905 Free PMC article.
Discovery of potent small-molecule inhibitors of lipoprotein(a) formation.
Diaz N, Perez C, Escribano AM, Sanz G, Priego J, Lafuente C, Barberis M, Calle L, Espinosa JF, Priest BT, Zhang HY, Nosie AK, Haas JV, Cannady E, Borel A, Schultze AE, Sauder JM, Hendle J, Weichert K, Nicholls SJ, Michael LF. Diaz N, et al. Among authors: nicholls sj. Nature. 2024 May 8. doi: 10.1038/s41586-024-07387-z. Online ahead of print. Nature. 2024. PMID: 38720069
Obicetrapib on Top of Maximally Tolerated Lipid-Modifying Therapies in Participants With or at High Risk for Atherosclerotic Cardiovascular Disease: Rationale and Designs of BROADWAY and BROOKLYN.
Nicholls SJ, Nelson AJ, Ditmarsch M, Kastelein JJP, Ballantyne CM, Ray KK, Navar AM, Nissen SE, Golberg AC, Brunham LR, Curcio D, Wuerdeman E, Neild A, Kling D, Hsieh A, Dicklin MR, Ference BA, Laufs U, Banach M, Mehran R, Catapano AL, Davidson MH. Nicholls SJ, et al. Am Heart J. 2024 May 3:S0002-8703(24)00116-9. doi: 10.1016/j.ahj.2024.05.002. Online ahead of print. Am Heart J. 2024. PMID: 38705341 Free article.
Glucagon-like Peptide-1 analogues and delipidation of coronary atheroma in statin-treated type 2 diabetic patients with coronary artery disease: The prespecified sub-analysis of the OPTIMAL randomized clinical trial.
Kataoka Y, Kitahara S, Funabashi S, Makino H, Matsubara M, Matsuo M, Omura-Ohata Y, Koezuka R, Tochiya M, Tamanaha T, Tomita T, Honda-Kohmo K, Noguchi M, Murai K, Sawada K, Iwai T, Matama H, Honda S, Fujino M, Nakao K, Yoneda S, Takagi K, Otsuka F, Asaumi Y, Hosoda K, Nicholls SJ, Yasuda S, Noguchi T. Kataoka Y, et al. Among authors: nicholls sj. Atheroscler Plus. 2024 Apr 4;56:1-6. doi: 10.1016/j.athplu.2024.03.001. eCollection 2024 Jun. Atheroscler Plus. 2024. PMID: 38617596 Free PMC article.
608 results