Nguyen-Tran VTB - Search Results

1

α/Sulfono-γ-AA peptide hybrids agonist of GLP-1R with prolonged action both in vitro and in vivo.

Shi Y, Lee C, Sang P, Amso Z, Huang D, Zhong W, Gu M, Wei L, Nguyen-Tran VTB, Zhang J, Shen W, Cai J. Shi Y, et al. Among authors: nguyen tran vtb. Acta Pharm Sin B. 2023 Apr;13(4):1648-1659. doi: 10.1016/j.apsb.2022.10.014. Epub 2022 Oct 21. Acta Pharm Sin B. 2023. PMID: 37139407 Free PMC article.

2

PPAR{delta} agonism activates fatty acid oxidation via PGC-1{alpha} but does not increase mitochondrial gene expression and function.

Kleiner S, Nguyen-Tran V, Baré O, Huang X, Spiegelman B, Wu Z. Kleiner S, et al. J Biol Chem. 2009 Jul 10;284(28):18624-33. doi: 10.1074/jbc.M109.008797. Epub 2009 May 12. J Biol Chem. 2009. PMID: 19435887 Free PMC article.

3

Characterization of a novel, brain-penetrating CB1 receptor inverse agonist: metabolic profile in diet-induced obese models and aspects of central activity.

Jacobson LH, Commerford SR, Gerber SP, Chen YA, Dardik B, Chaperon F, Schwartzkopf C, Nguyen-Tran V, Hollenbeck T, McNamara P, He X, Liu H, Seidel HM, Jaton AL, Gromada J, Teixeira S. Jacobson LH, et al. Naunyn Schmiedebergs Arch Pharmacol. 2011 Dec;384(6):565-81. doi: 10.1007/s00210-011-0686-y. Epub 2011 Sep 25. Naunyn Schmiedebergs Arch Pharmacol. 2011. PMID: 21947251

4

Multifunctional Antibody Agonists Targeting Glucagon-like Peptide-1, Glucagon, and Glucose-Dependent Insulinotropic Polypeptide Receptors.

Wang Y, Du J, Zou H, Liu Y, Zhang Y, Gonzalez J, Chao E, Lu L, Yang P, Parker H, Nguyen-Tran V, Shen W, Wang D, Schultz PG, Wang F. Wang Y, et al. Angew Chem Int Ed Engl. 2016 Sep 26;55(40):12475-8. doi: 10.1002/anie.201606321. Epub 2016 Sep 6. Angew Chem Int Ed Engl. 2016. PMID: 27595986

5

Rational Design of Dual Agonist-Antibody Fusions as Long-acting Therapeutic Hormones.

Liu Y, Wang Y, Zhang Y, Liu T, Jia H, Zou H, Fu Q, Zhang Y, Lu L, Chao E, Parker H, Nguyen-Tran V, Shen W, Wang D, Schultz PG, Wang F. Liu Y, et al. ACS Chem Biol. 2016 Nov 18;11(11):2991-2995. doi: 10.1021/acschembio.6b00630. Epub 2016 Oct 5. ACS Chem Biol. 2016. PMID: 27704775 Free PMC article.

6

Design of a Long-Acting and Selective MEG-Fatty Acid Stapled Prolactin-Releasing Peptide Analog.

Pflimlin E, Lear S, Lee C, Yu S, Zou H, To A, Joseph S, Nguyen-Tran V, Tremblay MS, Shen W. Pflimlin E, et al. ACS Med Chem Lett. 2019 Jul 5;10(8):1166-1172. doi: 10.1021/acsmedchemlett.9b00182. eCollection 2019 Aug 8. ACS Med Chem Lett. 2019. PMID: 31413801 Free PMC article.

7

Neratinib protects pancreatic beta cells in diabetes.

Ardestani A, Li S, Annamalai K, Lupse B, Geravandi S, Dobrowolski A, Yu S, Zhu S, Baguley TD, Surakattula M, Oetjen J, Hauberg-Lotte L, Herranz R, Awal S, Altenhofen D, Nguyen-Tran V, Joseph S, Schultz PG, Chatterjee AK, Rogers N, Tremblay MS, Shen W, Maedler K. Ardestani A, et al. Nat Commun. 2019 Nov 1;10(1):5015. doi: 10.1038/s41467-019-12880-5. Nat Commun. 2019. PMID: 31676778 Free PMC article.

8

Engineering a Potent, Long-Acting, and Periphery-Restricted Oxytocin Receptor Agonist with Anorexigenic and Body Weight Reducing Effects.

Pflimlin E, Zhou Z, Amso Z, Fu Q, Lee C, Muppiddi A, Joseph SB, Nguyen-Tran V, Shen W. Pflimlin E, et al. J Med Chem. 2020 Jan 9;63(1):382-390. doi: 10.1021/acs.jmedchem.9b01862. Epub 2019 Dec 18. J Med Chem. 2020. PMID: 31850759

9

New Generation Oxyntomodulin Peptides with Improved Pharmacokinetic Profiles Exhibit Weight Reducing and Anti-Steatotic Properties in Mice.

Yang PY, Zou H, Amso Z, Lee C, Huang D, Woods AK, Nguyen-Tran VTB, Schultz PG, Shen W. Yang PY, et al. Among authors: nguyen tran vtb. Bioconjug Chem. 2020 Apr 15;31(4):1167-1176. doi: 10.1021/acs.bioconjchem.0c00093. Epub 2020 Apr 3. Bioconjug Chem. 2020. PMID: 32243137

10

The activity of sulfono-γ-AApeptide helical foldamers that mimic GLP-1.

Sang P, Zhou Z, Shi Y, Lee C, Amso Z, Huang D, Odom T, Nguyen-Tran VTB, Shen W, Cai J. Sang P, et al. Among authors: nguyen tran vtb. Sci Adv. 2020 May 15;6(20):eaaz4988. doi: 10.1126/sciadv.aaz4988. eCollection 2020 May. Sci Adv. 2020. PMID: 32440547 Free PMC article.

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