Ng VHE - Search Results

1

Core-binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis.

Guo M, Chan THM, Zhou Q, An O, Li Y, Song Y, Tan ZH, Ng VHE, Peramangalam PS, Tan ZQ, Cao X, Iwanaga E, Matsuoka M, Ooi MGM, Jen WY, Koh LP, Chan E, Tan LK, Goh Y, Wang W, Koh BTH, Chun CM, Fullwood MJ, Chng WJ, Osato M, Pulikkan JA, Yang H, Chen L, Tenen DG. Guo M, et al. Among authors: ng vhe. Blood. 2023 Jun 22;141(25):3078-3090. doi: 10.1182/blood.2022015830. Blood. 2023. PMID: 36796022

2

Multilayered control of splicing regulatory networks by DAP3 leads to widespread alternative splicing changes in cancer.

Han J, An O, Ren X, Song Y, Tang SJ, Shen H, Ke X, Ng VHE, Tay DJT, Tan HQ, Kappei D, Yang H, Chen L. Han J, et al. Among authors: ng vhe. Nat Commun. 2022 Apr 4;13(1):1793. doi: 10.1038/s41467-022-29400-7. Nat Commun. 2022. PMID: 35379802 Free PMC article.

3

ADARs act as potent regulators of circular transcriptome in cancer.

Shen H, An O, Ren X, Song Y, Tang SJ, Ke XY, Han J, Tay DJT, Ng VHE, Molias FB, Pitcheshwar P, Leong KW, Tan KK, Yang H, Chen L. Shen H, et al. Among authors: ng vhe. Nat Commun. 2022 Mar 21;13(1):1508. doi: 10.1038/s41467-022-29138-2. Nat Commun. 2022. PMID: 35314703 Free PMC article.

4

Antisense RNAs Influence Promoter Usage of Their Counterpart Sense Genes in Cancer.

Bellido Molias F, Sim A, Leong KW, An O, Song Y, Ng VHE, Lim MWJ, Ying C, Teo JXJ, Göke J, Chen L. Bellido Molias F, et al. Among authors: ng vhe. Cancer Res. 2021 Dec 1;81(23):5849-5861. doi: 10.1158/0008-5472.CAN-21-1859. Epub 2021 Oct 14. Cancer Res. 2021. PMID: 34649947 Free PMC article.

5

RNA editing mediates the functional switch of COPA in a novel mechanism of hepatocarcinogenesis.

Song Y, An O, Ren X, Chan THM, Tay DJT, Tang SJ, Han J, Hong H, Ng VHE, Ke X, Shen H, Pitcheshwar P, Lin JS, Leong KW, Molias FB, Yang H, Kappei D, Chen L. Song Y, et al. Among authors: ng vhe. J Hepatol. 2021 Jan;74(1):135-147. doi: 10.1016/j.jhep.2020.07.021. Epub 2020 Jul 18. J Hepatol. 2021. PMID: 32693003 Free article.

6

Suppression of adenosine-to-inosine (A-to-I) RNA editome by death associated protein 3 (DAP3) promotes cancer progression.

Han J, An O, Hong H, Chan THM, Song Y, Shen H, Tang SJ, Lin JS, Ng VHE, Tay DJT, Molias FB, Pitcheshwar P, Tan HQ, Yang H, Chen L. Han J, et al. Among authors: ng vhe. Sci Adv. 2020 Jun 17;6(25):eaba5136. doi: 10.1126/sciadv.aba5136. eCollection 2020 Jun. Sci Adv. 2020. PMID: 32596459 Free PMC article.

7

Cis- and trans-regulations of pre-mRNA splicing by RNA editing enzymes influence cancer development.

Tang SJ, Shen H, An O, Hong H, Li J, Song Y, Han J, Tay DJT, Ng VHE, Bellido Molias F, Leong KW, Pitcheshwar P, Yang H, Chen L. Tang SJ, et al. Among authors: ng vhe. Nat Commun. 2020 Feb 7;11(1):799. doi: 10.1038/s41467-020-14621-5. Nat Commun. 2020. PMID: 32034135 Free PMC article.

8

Bidirectional regulation of adenosine-to-inosine (A-to-I) RNA editing by DEAH box helicase 9 (DHX9) in cancer.

Hong H, An O, Chan THM, Ng VHE, Kwok HS, Lin JS, Qi L, Han J, Tay DJT, Tang SJ, Yang H, Song Y, Bellido Molias F, Tenen DG, Chen L. Hong H, et al. Among authors: ng vhe. Nucleic Acids Res. 2018 Sep 6;46(15):7953-7969. doi: 10.1093/nar/gky396. Nucleic Acids Res. 2018. PMID: 29796672 Free PMC article.

9

An RNA editing/dsRNA binding-independent gene regulatory mechanism of ADARs and its clinical implication in cancer.

Qi L, Song Y, Chan THM, Yang H, Lin CH, Tay DJT, Hong H, Tang SJ, Tan KT, Huang XX, Lin JS, Ng VHE, Maury JJP, Tenen DG, Chen L. Qi L, et al. Among authors: ng vhe. Nucleic Acids Res. 2017 Oct 13;45(18):10436-10451. doi: 10.1093/nar/gkx667. Nucleic Acids Res. 2017. PMID: 28985428 Free PMC article.

10

ADAR-Mediated RNA Editing Predicts Progression and Prognosis of Gastric Cancer.

Chan TH, Qamra A, Tan KT, Guo J, Yang H, Qi L, Lin JS, Ng VH, Song Y, Hong H, Tay ST, Liu Y, Lee J, Rha SY, Zhu F, So JB, Teh BT, Yeoh KG, Rozen S, Tenen DG, Tan P, Chen L. Chan TH, et al. Gastroenterology. 2016 Oct;151(4):637-650.e10. doi: 10.1053/j.gastro.2016.06.043. Epub 2016 Jul 1. Gastroenterology. 2016. PMID: 27373511 Free PMC article.

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