Ng PK - Search Results

1

Naturally occurring neomorphic PIK3R1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitors.

Cheung LW, Yu S, Zhang D, Li J, Ng PK, Panupinthu N, Mitra S, Ju Z, Yu Q, Liang H, Hawke DH, Lu Y, Broaddus RR, Mills GB. Cheung LW, et al. Among authors: ng pk. Cancer Cell. 2014 Oct 13;26(4):479-94. doi: 10.1016/j.ccell.2014.08.017. Epub 2014 Oct 2. Cancer Cell. 2014. PMID: 25284480 Free PMC article.

2

Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies.

Ip CKM, Ng PKS, Jeong KJ, Shao SH, Ju Z, Leonard PG, Hua X, Vellano CP, Woessner R, Sahni N, Scott KL, Mills GB. Ip CKM, et al. Nat Commun. 2018 Nov 2;9(1):4583. doi: 10.1038/s41467-018-06949-w. Nat Commun. 2018. PMID: 30389923 Free PMC article.

3

Cancer-associated mutations in the p85α N-terminal SH2 domain activate a spectrum of receptor tyrosine kinases.

Li X, Lau AYT, Ng ASN, Aldehaiman A, Zhou Y, Ng PKS, Arold ST, Cheung LWT. Li X, et al. Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):e2101751118. doi: 10.1073/pnas.2101751118. Proc Natl Acad Sci U S A. 2021. PMID: 34507989 Free PMC article.

4

Therapeutic implications of activating noncanonical PIK3CA mutations in head and neck squamous cell carcinoma.

Jin N, Keam B, Cho J, Lee MJ, Kim HR, Torosyan H, Jura N, Ng PK, Mills GB, Li H, Zeng Y, Barbash Z, Tarcic G, Kang H, Bauman JE, Kim MO, VanLandingham NK, Swaney DL, Krogan NJ, Johnson DE, Grandis JR. Jin N, et al. Among authors: ng pk. J Clin Invest. 2021 Nov 15;131(22):e150335. doi: 10.1172/JCI150335. J Clin Invest. 2021. PMID: 34779417 Free PMC article.

5

Efficacy of futibatinib, an irreversible fibroblast growth factor receptor inhibitor, in FGFR-altered breast cancer.

Saridogan T, Akcakanat A, Zhao M, Evans KW, Yuca E, Scott S, Kirby BP, Zheng X, Ha MJ, Chen H, Ng PKS, DiPeri TP, Mills GB, Rodon Ahnert J, Damodaran S, Meric-Bernstam F. Saridogan T, et al. Among authors: ng pks. Sci Rep. 2023 Nov 18;13(1):20223. doi: 10.1038/s41598-023-46586-y. Sci Rep. 2023. PMID: 37980453 Free PMC article.

6

Molecular Landscape of BRAF-Mutant NSCLC Reveals an Association Between Clonality and Driver Mutations and Identifies Targetable Non-V600 Driver Mutations.

Negrao MV, Raymond VM, Lanman RB, Robichaux JP, He J, Nilsson MB, Ng PKS, Amador BE, Roarty EB, Nagy RJ, Banks KC, Zhu VW, Ng C, Chae YK, Clarke JM, Crawford JA, Meric-Bernstam F, Ignatius Ou SH, Gandara DR, Heymach JV, Bivona TG, McCoach CE. Negrao MV, et al. J Thorac Oncol. 2020 Oct;15(10):1611-1623. doi: 10.1016/j.jtho.2020.05.021. Epub 2020 Jun 13. J Thorac Oncol. 2020. PMID: 32540409 Free PMC article.

7

RAC1 Alterations Induce Acquired Dabrafenib Resistance in Association with Anaplastic Transformation in a Papillary Thyroid Cancer Patient.

Bagheri-Yarmand R, Busaidy NL, McBeath E, Danysh BP, Evans KW, Moss TJ, Akcakanat A, Ng PKS, Knippler CM, Golden JA, Williams MD, Multani AS, Cabanillas ME, Shaw KR, Meric-Bernstam F, Shah MH, Ringel MD, Hofmann MC. Bagheri-Yarmand R, et al. Cancers (Basel). 2021 Sep 30;13(19):4950. doi: 10.3390/cancers13194950. Cancers (Basel). 2021. PMID: 34638434 Free PMC article.

8

Advances in Gluten Hypersensitivity: Novel Dietary-Based Therapeutics in Research and Development.

Jorgensen R, Devarahalli SS, Shah Y, Gao H, Arul Arasan TS, Ng PKW, Gangur V. Jorgensen R, et al. Among authors: ng pkw. Int J Mol Sci. 2024 Apr 16;25(8):4399. doi: 10.3390/ijms25084399. Int J Mol Sci. 2024. PMID: 38673984 Free PMC article. Review.

9

A TRIZ Approach for Designing a Smart Lighting and Control System for Classrooms Based on Counter Application with Dual PIR Sensors.

Chong PL, Ismail D, Ng PK, Kong FY, Basir Khan MR, Thirugnanam S. Chong PL, et al. Among authors: ng pk. Sensors (Basel). 2024 Feb 10;24(4):1177. doi: 10.3390/s24041177. Sensors (Basel). 2024. PMID: 38400335 Free PMC article.

10

On the systematic placement of the fossil crab Lathahypossia aculeata (Busulini, Tessier & Visentin, 1984) (Crustacea: Decapoda: Brachyura).

Oss L, Ng PKL. Oss L, et al. Among authors: ng pkl. Zootaxa. 2023 Sep 26;5351(2):265-275. doi: 10.11646/zootaxa.5351.2.4. Zootaxa. 2023. PMID: 38221490

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