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T Helper 2 IL-4/IL-13 Dual Blockade with Dupilumab Is Linked to Some Emergent T Helper 17‒Type Diseases, Including Seronegative Arthritis and Enthesitis/Enthesopathy, but Not to Humoral Autoimmune Diseases.
Bridgewood C, Wittmann M, Macleod T, Watad A, Newton D, Bhan K, Amital H, Damiani G, Giryes S, Bragazzi NL, McGonagle D. Bridgewood C, et al. Among authors: newton d. J Invest Dermatol. 2022 Oct;142(10):2660-2667. doi: 10.1016/j.jid.2022.03.013. Epub 2022 Apr 6. J Invest Dermatol. 2022. PMID: 35395222 Free article.
Evidence that tissue resident human enthesis γδT-cells can produce IL-17A independently of IL-23R transcript expression.
Cuthbert RJ, Watad A, Fragkakis EM, Dunsmuir R, Loughenbury P, Khan A, Millner PA, Davison A, Marzo-Ortega H, Newton D, Bridgewood C, McGonagle DG. Cuthbert RJ, et al. Among authors: newton d. Ann Rheum Dis. 2019 Nov;78(11):1559-1565. doi: 10.1136/annrheumdis-2019-215210. Epub 2019 Sep 17. Ann Rheum Dis. 2019. PMID: 31530557 Free PMC article.
Normal human enthesis harbours conventional CD4+ and CD8+ T cells with regulatory features and inducible IL-17A and TNF expression.
Watad A, Rowe H, Russell T, Zhou Q, Anderson LK, Khan A, Dunsmuir R, Loughenbury P, Borse V, Rao A, Millner PA, Bragazzi NL, Amital H, Cuhtbert R, Wittmann M, Sharif K, Kenna T, Brown MA, Newton D, Bridgewood C, McGonagle DG. Watad A, et al. Among authors: newton d. Ann Rheum Dis. 2020 Aug;79(8):1044-1054. doi: 10.1136/annrheumdis-2020-217309. Epub 2020 May 13. Ann Rheum Dis. 2020. PMID: 32404344 Free PMC article.
Characterization of Blood Mucosal-Associated Invariant T Cells in Patients With Axial Spondyloarthritis and of Resident Mucosal-Associated Invariant T Cells From the Axial Entheses of Non-Axial Spondyloarthritis Control Patients.
Rosine N, Rowe H, Koturan S, Yahia-Cherbal H, Leloup C, Watad A, Berenbaum F, Sellam J, Dougados M, Aimanianda V, Cuthbert R, Bridgewood C, Newton D, Bianchi E, Rogge L, McGonagle D, Miceli-Richard C. Rosine N, et al. Among authors: newton d. Arthritis Rheumatol. 2022 Nov;74(11):1786-1795. doi: 10.1002/art.42090. Epub 2022 Sep 22. Arthritis Rheumatol. 2022. PMID: 35166073 Free PMC article.
Effectiveness of SARS-CoV-2 vaccination in patients with rheumatoid arthritis (RA) on DMARDs: as determined by antibody and T cell responses.
Saleem B, Ross RL, Bissell LA, Aslam A, Mankia K, Duquenne L, Corsadden D, Carter C, Hughes P, Nadat FA, Mulipa P, Lobb M, Clarke B, Mbara K, Morton R, Dibb S, Chowdhury R, Newton D, Pike A, Kakkar V, Savic S, DelGaldo F, Emery P. Saleem B, et al. Among authors: newton d. RMD Open. 2022 Mar;8(1):e002050. doi: 10.1136/rmdopen-2021-002050. RMD Open. 2022. PMID: 35365569 Free PMC article.
Patients with paroxysmal nocturnal hemoglobinuria demonstrate a prothrombotic clotting phenotype which is improved by complement inhibition with eculizumab.
Macrae FL, Peacock-Young B, Bowman P, Baker SR, Quested S, Linton E, Hillmen P, Griffin M, Munir T, Payne D, McKinley C, Clarke D, Newton DJ, Hill A, Ariëns RAS. Macrae FL, et al. Among authors: newton dj. Am J Hematol. 2020 Aug;95(8):944-952. doi: 10.1002/ajh.25841. Epub 2020 May 11. Am J Hematol. 2020. PMID: 32311169 Free article.
784 results