Nettles KW - Search Results

1

Ligand control of coregulator recruitment to nuclear receptors.

Nettles KW, Greene GL. Nettles KW, et al. Annu Rev Physiol. 2005;67:309-33. doi: 10.1146/annurev.physiol.66.032802.154710. Annu Rev Physiol. 2005. PMID: 15709961 Review.

2

Nuclear receptor ligands and cofactor recruitment: is there a coactivator "on deck"?

Nettles KW, Greene GL. Nettles KW, et al. Mol Cell. 2003 Apr;11(4):850-1. doi: 10.1016/s1097-2765(03)00133-3. Mol Cell. 2003. PMID: 12718871 Free article. Review.

3

Allosteric control of ligand selectivity between estrogen receptors alpha and beta: implications for other nuclear receptors.

Nettles KW, Sun J, Radek JT, Sheng S, Rodriguez AL, Katzenellenbogen JA, Katzenellenbogen BS, Greene GL. Nettles KW, et al. Mol Cell. 2004 Feb 13;13(3):317-27. doi: 10.1016/s1097-2765(04)00054-1. Mol Cell. 2004. PMID: 14967140 Free article.

4

Structural plasticity in the oestrogen receptor ligand-binding domain.

Nettles KW, Bruning JB, Gil G, O'Neill EE, Nowak J, Guo Y, Kim Y, DeSombre ER, Dilis R, Hanson RN, Joachimiak A, Greene GL. Nettles KW, et al. EMBO Rep. 2007 Jun;8(6):563-8. doi: 10.1038/sj.embor.7400963. Epub 2007 Apr 27. EMBO Rep. 2007. PMID: 17468738 Free PMC article.

5

CBP Is a dosage-dependent regulator of nuclear factor-kappaB suppression by the estrogen receptor.

Nettles KW, Gil G, Nowak J, Métivier R, Sharma VB, Greene GL. Nettles KW, et al. Mol Endocrinol. 2008 Feb;22(2):263-72. doi: 10.1210/me.2007-0324. Epub 2007 Oct 11. Mol Endocrinol. 2008. PMID: 17932106 Free PMC article.

6

NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses.

Nettles KW, Bruning JB, Gil G, Nowak J, Sharma SK, Hahm JB, Kulp K, Hochberg RB, Zhou H, Katzenellenbogen JA, Katzenellenbogen BS, Kim Y, Joachmiak A, Greene GL. Nettles KW, et al. Nat Chem Biol. 2008 Apr;4(4):241-7. doi: 10.1038/nchembio.76. Epub 2008 Mar 16. Nat Chem Biol. 2008. PMID: 18344977 Free PMC article.

7

A structural explanation for ERalpha/ERbeta SERM discrimination.

Greene GL, Shiau AK, Nettles KW. Greene GL, et al. Among authors: nettles kw. Ernst Schering Res Found Workshop. 2004;(46):33-45. doi: 10.1007/978-3-662-05386-7_3. Ernst Schering Res Found Workshop. 2004. PMID: 15248503 Review.

8

Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism.

Shiau AK, Barstad D, Radek JT, Meyers MJ, Nettles KW, Katzenellenbogen BS, Katzenellenbogen JA, Agard DA, Greene GL. Shiau AK, et al. Among authors: nettles kw. Nat Struct Biol. 2002 May;9(5):359-64. doi: 10.1038/nsb787. Nat Struct Biol. 2002. PMID: 11953755

9

Structure-guided optimization of estrogen receptor binding affinity and antagonist potency of pyrazolopyrimidines with basic side chains.

Zhou HB, Sheng S, Compton DR, Kim Y, Joachimiak A, Sharma S, Carlson KE, Katzenellenbogen BS, Nettles KW, Greene GL, Katzenellenbogen JA. Zhou HB, et al. Among authors: nettles kw. J Med Chem. 2007 Jan 25;50(2):399-403. doi: 10.1021/jm061035y. J Med Chem. 2007. PMID: 17228884

10

Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands.

Zhou HB, Nettles KW, Bruning JB, Kim Y, Joachimiak A, Sharma S, Carlson KE, Stossi F, Katzenellenbogen BS, Greene GL, Katzenellenbogen JA. Zhou HB, et al. Among authors: nettles kw. Chem Biol. 2007 Jun;14(6):659-69. doi: 10.1016/j.chembiol.2007.04.009. Chem Biol. 2007. PMID: 17584613

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