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Genetic and pharmacological inhibition of XBP1 protects against APAP hepatotoxicity through the activation of autophagy.
Ye H, Chen C, Wu H, Zheng K, Martín-Adrados B, Caparros E, Francés R, Nelson LJ, Gómez Del Moral M, Asensio I, Vaquero J, Bañares R, Ávila MA, Andrade RJ, Isabel Lucena M, Martínez-Chantar ML, Reeves HL, Masson S, Blumberg RS, Gracia-Sancho J, Nevzorova YA, Martínez-Naves E, Cubero FJ. Ye H, et al. Among authors: nelson lj. Cell Death Dis. 2022 Feb 10;13(2):143. doi: 10.1038/s41419-022-04580-8. Cell Death Dis. 2022. PMID: 35145060 Free PMC article.
Krüppel-like factor 6 is a transcriptional activator of autophagy in acute liver injury.
Sydor S, Manka P, Best J, Jafoui S, Sowa JP, Zoubek ME, Hernandez-Gea V, Cubero FJ, Kälsch J, Vetter D, Fiel MI, Hoshida Y, Bian CB, Nelson LJ, Moshage H, Faber KN, Paul A, Baba HA, Gerken G, Friedman SL, Canbay A, Bechmann LP. Sydor S, et al. Among authors: nelson lj. Sci Rep. 2017 Aug 14;7(1):8119. doi: 10.1038/s41598-017-08680-w. Sci Rep. 2017. PMID: 28808340 Free PMC article.
Dissecting the molecular pathophysiology of drug-induced liver injury.
Ye H, Nelson LJ, Gómez Del Moral M, Martínez-Naves E, Cubero FJ. Ye H, et al. Among authors: nelson lj. World J Gastroenterol. 2018 Apr 7;24(13):1373-1385. doi: 10.3748/wjg.v24.i13.1373. World J Gastroenterol. 2018. PMID: 29632419 Free PMC article. Review.
Alcoholic liver disease: Utility of animal models.
Lamas-Paz A, Hao F, Nelson LJ, Vázquez MT, Canals S, Gómez Del Moral M, Martínez-Naves E, Nevzorova YA, Cubero FJ. Lamas-Paz A, et al. Among authors: nelson lj. World J Gastroenterol. 2018 Dec 7;24(45):5063-5075. doi: 10.3748/wjg.v24.i45.5063. World J Gastroenterol. 2018. PMID: 30568384 Free PMC article. Review.
Dual Targeting of G9a and DNA Methyltransferase-1 for the Treatment of Experimental Cholangiocarcinoma.
Colyn L, Bárcena-Varela M, Álvarez-Sola G, Latasa MU, Uriarte I, Santamaría E, Herranz JM, Santos-Laso A, Arechederra M, Ruiz de Gauna M, Aspichueta P, Canale M, Casadei-Gardini A, Francesconi M, Carotti S, Morini S, Nelson LJ, Iraburu MJ, Chen C, Sangro B, Marin JJG, Martinez-Chantar ML, Banales JM, Arnes-Benito R, Huch M, Patino JM, Dar AA, Nosrati M, Oyarzábal J, Prósper F, Urman J, Cubero FJ, Trautwein C, Berasain C, Fernandez-Barrena MG, Avila MA. Colyn L, et al. Among authors: nelson lj. Hepatology. 2021 Jun;73(6):2380-2396. doi: 10.1002/hep.31642. Hepatology. 2021. PMID: 33222246
Advanced preclinical models for evaluation of drug-induced liver injury - consensus statement by the European Drug-Induced Liver Injury Network [PRO-EURO-DILI-NET].
Fernandez-Checa JC, Bagnaninchi P, Ye H, Sancho-Bru P, Falcon-Perez JM, Royo F, Garcia-Ruiz C, Konu O, Miranda J, Lunov O, Dejneka A, Elfick A, McDonald A, Sullivan GJ, Aithal GP, Lucena MI, Andrade RJ, Fromenty B, Kranendonk M, Cubero FJ, Nelson LJ. Fernandez-Checa JC, et al. Among authors: nelson lj. J Hepatol. 2021 Oct;75(4):935-959. doi: 10.1016/j.jhep.2021.06.021. Epub 2021 Jun 24. J Hepatol. 2021. PMID: 34171436 Free article. Review.
182 results