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Enhanced prime editing systems by manipulating cellular determinants of editing outcomes.
Chen PJ, Hussmann JA, Yan J, Knipping F, Ravisankar P, Chen PF, Chen C, Nelson JW, Newby GA, Sahin M, Osborn MJ, Weissman JS, Adamson B, Liu DR. Chen PJ, et al. Among authors: nelson jw. Cell. 2021 Oct 28;184(22):5635-5652.e29. doi: 10.1016/j.cell.2021.09.018. Epub 2021 Oct 14. Cell. 2021. PMID: 34653350 Free PMC article.
Engineered pegRNAs improve prime editing efficiency.
Nelson JW, Randolph PB, Shen SP, Everette KA, Chen PJ, Anzalone AV, An M, Newby GA, Chen JC, Hsu A, Liu DR. Nelson JW, et al. Nat Biotechnol. 2022 Mar;40(3):402-410. doi: 10.1038/s41587-021-01039-7. Epub 2021 Oct 4. Nat Biotechnol. 2022. PMID: 34608327 Free PMC article.
Author Correction: Engineered pegRNAs improve prime editing efficiency.
Nelson JW, Randolph PB, Shen SP, Everette KA, Chen PJ, Anzalone AV, An M, Newby GA, Chen JC, Hsu A, Liu DR. Nelson JW, et al. Nat Biotechnol. 2022 Mar;40(3):432. doi: 10.1038/s41587-021-01175-0. Nat Biotechnol. 2022. PMID: 34880468 No abstract available.
Gramicidin D enhances the antibacterial activity of fluoride.
Nelson JW, Zhou Z, Breaker RR. Nelson JW, et al. Bioorg Med Chem Lett. 2014 Jul 1;24(13):2969-2971. doi: 10.1016/j.bmcl.2014.03.061. Epub 2014 Mar 28. Bioorg Med Chem Lett. 2014. PMID: 24857543 Free PMC article.
Control of bacterial exoelectrogenesis by c-AMP-GMP.
Nelson JW, Sudarsan N, Phillips GE, Stav S, Lünse CE, McCown PJ, Breaker RR. Nelson JW, et al. Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):5389-94. doi: 10.1073/pnas.1419264112. Epub 2015 Apr 6. Proc Natl Acad Sci U S A. 2015. PMID: 25848023 Free PMC article.
The Biology of Free Guanidine As Revealed by Riboswitches.
Breaker RR, Atilho RM, Malkowski SN, Nelson JW, Sherlock ME. Breaker RR, et al. Among authors: nelson jw. Biochemistry. 2017 Jan 17;56(2):345-347. doi: 10.1021/acs.biochem.6b01269. Epub 2017 Jan 6. Biochemistry. 2017. PMID: 28060483 Free PMC article.
Small molecule fluoride toxicity agonists.
Nelson JW, Plummer MS, Blount KF, Ames TD, Breaker RR. Nelson JW, et al. Chem Biol. 2015 Apr 23;22(4):527-534. doi: 10.1016/j.chembiol.2015.03.016. Chem Biol. 2015. PMID: 25910244 Free PMC article.
The lost language of the RNA World.
Nelson JW, Breaker RR. Nelson JW, et al. Sci Signal. 2017 Jun 13;10(483):eaam8812. doi: 10.1126/scisignal.aam8812. Sci Signal. 2017. PMID: 28611182 Free PMC article. Review.
229 results