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Blood-brain barrier breakdown is an early biomarker of human cognitive dysfunction.
Nation DA, Sweeney MD, Montagne A, Sagare AP, D'Orazio LM, Pachicano M, Sepehrband F, Nelson AR, Buennagel DP, Harrington MG, Benzinger TLS, Fagan AM, Ringman JM, Schneider LS, Morris JC, Chui HC, Law M, Toga AW, Zlokovic BV. Nation DA, et al. Among authors: nelson ar. Nat Med. 2019 Feb;25(2):270-276. doi: 10.1038/s41591-018-0297-y. Epub 2019 Jan 14. Nat Med. 2019. PMID: 30643288 Free PMC article.
GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration.
Winkler EA, Nishida Y, Sagare AP, Rege SV, Bell RD, Perlmutter D, Sengillo JD, Hillman S, Kong P, Nelson AR, Sullivan JS, Zhao Z, Meiselman HJ, Wendy RB, Soto J, Abel ED, Makshanoff J, Zuniga E, De Vivo DC, Zlokovic BV. Winkler EA, et al. Among authors: nelson ar. Nat Neurosci. 2015 Apr;18(4):521-530. doi: 10.1038/nn.3966. Epub 2015 Mar 2. Nat Neurosci. 2015. PMID: 25730668 Free PMC article.
Establishment and Dysfunction of the Blood-Brain Barrier.
Zhao Z, Nelson AR, Betsholtz C, Zlokovic BV. Zhao Z, et al. Among authors: nelson ar. Cell. 2015 Nov 19;163(5):1064-1078. doi: 10.1016/j.cell.2015.10.067. Cell. 2015. PMID: 26590417 Free PMC article. Review.
Role of clusterin in the brain vascular clearance of amyloid-β.
Nelson AR, Sagare AP, Zlokovic BV. Nelson AR, et al. Proc Natl Acad Sci U S A. 2017 Aug 15;114(33):8681-8682. doi: 10.1073/pnas.1711357114. Epub 2017 Aug 1. Proc Natl Acad Sci U S A. 2017. PMID: 28765369 Free PMC article. No abstract available.
Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.
Shi Y, Lin S, Staats KA, Li Y, Chang WH, Hung ST, Hendricks E, Linares GR, Wang Y, Son EY, Wen X, Kisler K, Wilkinson B, Menendez L, Sugawara T, Woolwine P, Huang M, Cowan MJ, Ge B, Koutsodendris N, Sandor KP, Komberg J, Vangoor VR, Senthilkumar K, Hennes V, Seah C, Nelson AR, Cheng TY, Lee SJ, August PR, Chen JA, Wisniewski N, Hanson-Smith V, Belgard TG, Zhang A, Coba M, Grunseich C, Ward ME, van den Berg LH, Pasterkamp RJ, Trotti D, Zlokovic BV, Ichida JK. Shi Y, et al. Among authors: nelson ar. Nat Med. 2018 Mar;24(3):313-325. doi: 10.1038/nm.4490. Epub 2018 Feb 5. Nat Med. 2018. PMID: 29400714 Free PMC article.
217 results