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CDK2 regulates HIV-1 transcription by phosphorylation of CDK9 on serine 90.
Breuer D, Kotelkin A, Ammosova T, Kumari N, Ivanov A, Ilatovskiy AV, Beullens M, Roane PR, Bollen M, Petukhov MG, Kashanchi F, Nekhai S. Breuer D, et al. Among authors: nekhai s. Retrovirology. 2012 Nov 9;9:94. doi: 10.1186/1742-4690-9-94. Retrovirology. 2012. PMID: 23140174 Free PMC article.
Role of protein phosphatase 1 in dephosphorylation of Ebola virus VP30 protein and its targeting for the inhibition of viral transcription.
Ilinykh PA, Tigabu B, Ivanov A, Ammosova T, Obukhov Y, Garron T, Kumari N, Kovalskyy D, Platonov MO, Naumchik VS, Freiberg AN, Nekhai S, Bukreyev A. Ilinykh PA, et al. Among authors: nekhai s. J Biol Chem. 2014 Aug 15;289(33):22723-22738. doi: 10.1074/jbc.M114.575050. Epub 2014 Jun 16. J Biol Chem. 2014. PMID: 24936058 Free PMC article.
Phenyl-1-Pyridin-2yl-ethanone-based iron chelators increase IκB-α expression, modulate CDK2 and CDK9 activities, and inhibit HIV-1 transcription.
Kumari N, Iordanskiy S, Kovalskyy D, Breuer D, Niu X, Lin X, Xu M, Gavrilenko K, Kashanchi F, Dhawan S, Nekhai S. Kumari N, et al. Among authors: nekhai s. Antimicrob Agents Chemother. 2014 Nov;58(11):6558-71. doi: 10.1128/AAC.02918-14. Epub 2014 Aug 25. Antimicrob Agents Chemother. 2014. PMID: 25155598 Free PMC article.
166 results