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Robust self-supervised denoising of voltage imaging data using CellMincer.
Wang B, Ma T, Chen T, Nguyen T, Crouse E, Fleming SJ, Walker AS, Valakh V, Nehme R, Miller EW, Farhi SL, Babadi M. Wang B, et al. Among authors: nehme r. bioRxiv [Preprint]. 2024 Apr 15:2024.04.12.589298. doi: 10.1101/2024.04.12.589298. bioRxiv. 2024. PMID: 38659950 Free PMC article. Preprint.
A systems-biology approach connects aging mechanisms with Alzheimer's disease pathogenesis.
Leventhal MJ, Zanella CA, Kang B, Peng J, Gritsch D, Liao Z, Bukhari H, Wang T, Pao PC, Danquah S, Benetatos J, Nehme R, Farhi S, Tsai LH, Dong X, Scherzer CR, Feany MB, Fraenkel E. Leventhal MJ, et al. Among authors: nehme r. bioRxiv [Preprint]. 2024 Mar 17:2024.03.17.585262. doi: 10.1101/2024.03.17.585262. bioRxiv. 2024. PMID: 38559190 Free PMC article. Preprint.
High-dimensional phenotyping to define the genetic basis of cellular morphology.
Tegtmeyer M, Arora J, Asgari S, Cimini BA, Nadig A, Peirent E, Liyanage D, Way GP, Weisbart E, Nathan A, Amariuta T, Eggan K, Haghighi M, McCarroll SA, O'Connor L, Carpenter AE, Singh S, Nehme R, Raychaudhuri S. Tegtmeyer M, et al. Among authors: nehme r. Nat Commun. 2024 Jan 6;15(1):347. doi: 10.1038/s41467-023-44045-w. Nat Commun. 2024. PMID: 38184653 Free PMC article.
Econazole selectively induces cell death in NF1-homozygous mutant tumor cells.
Lakes YB, Moye SL, Mo J, Tegtmeyer M, Nehme R, Charlton M, Salinas G, McKay RM, Eggan K, Le LQ. Lakes YB, et al. Among authors: nehme r. Cell Rep Med. 2023 Dec 19;4(12):101309. doi: 10.1016/j.xcrm.2023.101309. Epub 2023 Dec 11. Cell Rep Med. 2023. PMID: 38086379 Free PMC article.
Early Alzheimer's disease pathology in human cortex involves transient cell states.
Gazestani V, Kamath T, Nadaf NM, Dougalis A, Burris SJ, Rooney B, Junkkari A, Vanderburg C, Pelkonen A, Gomez-Budia M, Välimäki NN, Rauramaa T, Therrien M, Koivisto AM, Tegtmeyer M, Herukka SK, Abdulraouf A, Marsh SE, Hiltunen M, Nehme R, Malm T, Stevens B, Leinonen V, Macosko EZ. Gazestani V, et al. Among authors: nehme r. Cell. 2023 Sep 28;186(20):4438-4453.e23. doi: 10.1016/j.cell.2023.08.005. Cell. 2023. PMID: 37774681
Targeting intracellular galectins for cancer treatment.
Nehmé R, St-Pierre Y. Nehmé R, et al. Front Immunol. 2023 Sep 11;14:1269391. doi: 10.3389/fimmu.2023.1269391. eCollection 2023. Front Immunol. 2023. PMID: 37753083 Free PMC article. Review.
Robust induction of functional astrocytes using NGN2 expression in human pluripotent stem cells.
Berryer MH, Tegtmeyer M, Binan L, Valakh V, Nathanson A, Trendafilova D, Crouse E, Klein JA, Meyer D, Pietiläinen O, Rapino F, Farhi SL, Rubin LL, McCarroll SA, Nehme R, Barrett LE. Berryer MH, et al. Among authors: nehme r. iScience. 2023 May 30;26(7):106995. doi: 10.1016/j.isci.2023.106995. eCollection 2023 Jul 21. iScience. 2023. PMID: 37534135 Free PMC article.
118 results