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Bv8/prokineticin 2 is involved in Aβ-induced neurotoxicity.
Severini C, Lattanzi R, Maftei D, Marconi V, Ciotti MT, Petrocchi Passeri P, Florenzano F, Del Duca E, Caioli S, Zona C, Balboni G, Salvadori S, Nisticò R, Negri L. Severini C, et al. Among authors: negri l. Sci Rep. 2015 Oct 19;5:15301. doi: 10.1038/srep15301. Sci Rep. 2015. PMID: 26477583 Free PMC article.
Bv8/Prokineticin proteins and their receptors.
Negri L, Lattanzi R, Giannini E, Melchiorri P. Negri L, et al. Life Sci. 2007 Sep 15;81(14):1103-16. doi: 10.1016/j.lfs.2007.08.011. Epub 2007 Aug 17. Life Sci. 2007. PMID: 17881008 Review.
Prokineticin 2 upregulation in the peripheral nervous system has a major role in triggering and maintaining neuropathic pain in the chronic constriction injury model.
Lattanzi R, Maftei D, Marconi V, Florenzano F, Franchi S, Borsani E, Rodella LF, Balboni G, Salvadori S, Sacerdote P, Negri L. Lattanzi R, et al. Among authors: negri l. Biomed Res Int. 2015;2015:301292. doi: 10.1155/2015/301292. Epub 2015 Jan 5. Biomed Res Int. 2015. PMID: 25685780 Free PMC article.
Prokineticin system modulation as a new target to counteract the amyloid beta toxicity induced by glutamatergic alterations in an in vitro model of Alzheimer's disease.
Caioli S, Severini C, Ciotti T, Florenzano F, Pimpinella D, Petrocchi Passeri P, Balboni G, Polisca P, Lattanzi R, Nisticò R, Negri L, Zona C. Caioli S, et al. Among authors: negri l. Neuropharmacology. 2017 Apr;116:82-97. doi: 10.1016/j.neuropharm.2016.12.012. Epub 2016 Dec 15. Neuropharmacology. 2017. PMID: 27989680
The prokineticin receptor antagonist PC1 rescues memory impairment induced by β amyloid administration through the modulation of prokineticin system.
Maftei D, Ratano P, Fusco I, Marconi V, Squillace S, Negri L, Severini C, Balboni G, Steardo L, Bronzuoli MR, Scuderi C, Campolongo P, Lattanzi R. Maftei D, et al. Among authors: negri l. Neuropharmacology. 2019 Nov 1;158:107739. doi: 10.1016/j.neuropharm.2019.107739. Epub 2019 Aug 10. Neuropharmacology. 2019. PMID: 31408628
Controlling the activation of the Bv8/prokineticin system reduces neuroinflammation and abolishes thermal and tactile hyperalgesia in neuropathic animals.
Maftei D, Marconi V, Florenzano F, Giancotti LA, Castelli M, Moretti S, Borsani E, Rodella LF, Balboni G, Luongo L, Maione S, Sacerdote P, Negri L, Lattanzi R. Maftei D, et al. Among authors: negri l. Br J Pharmacol. 2014 Nov;171(21):4850-65. doi: 10.1111/bph.12793. Epub 2014 Sep 5. Br J Pharmacol. 2014. PMID: 24902717 Free PMC article.
331 results