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Page 1
Class I HDAC inhibitors enhance YB-1 acetylation and oxidative stress to block sarcoma metastasis.
El-Naggar AM, Somasekharan SP, Wang Y, Cheng H, Negri GL, Pan M, Wang XQ, Delaidelli A, Rafn B, Cran J, Zhang F, Zhang H, Colborne S, Gleave M, Mandinova A, Kedersha N, Hughes CS, Surdez D, Delattre O, Wang Y, Huntsman DG, Morin GB, Sorensen PH. El-Naggar AM, et al. Among authors: negri gl. EMBO Rep. 2019 Dec 5;20(12):e48375. doi: 10.15252/embr.201948375. Epub 2019 Oct 31. EMBO Rep. 2019. PMID: 31668005 Free PMC article.
Arginine Depletion Therapy with ADI-PEG20 Limits Tumor Growth in Argininosuccinate Synthase-Deficient Ovarian Cancer, Including Small-Cell Carcinoma of the Ovary, Hypercalcemic Type.
Ji JX, Cochrane DR, Tessier-Cloutier B, Chen SY, Ho G, Pathak KV, Alcazar IN, Farnell D, Leung S, Cheng A, Chow C, Colborne S, Negri GL, Kommoss F, Karnezis A, Morin GB, McAlpine JN, Gilks CB, Weissman BE, Trent JM, Hoang L, Pirrotte P, Wang Y, Huntsman DG. Ji JX, et al. Among authors: negri gl. Clin Cancer Res. 2020 Aug 15;26(16):4402-4413. doi: 10.1158/1078-0432.CCR-19-1905. Epub 2020 May 14. Clin Cancer Res. 2020. PMID: 32409304 Free PMC article.
Whole-proteome analysis of mesonephric-derived cancers describes new potential biomarkers.
Gibbard E, Cochrane DR, Pors J, Negri GL, Colborne S, Cheng AS, Chow C, Farnell D, Tessier-Cloutier B, McAlpine JN, Morin GB, Schmidt D, Kommoss S, Kommoss F, Keul J, Gilks B, Huntsman DG, Hoang L. Gibbard E, et al. Among authors: negri gl. Hum Pathol. 2021 Feb;108:1-11. doi: 10.1016/j.humpath.2020.10.005. Epub 2020 Oct 26. Hum Pathol. 2021. PMID: 33121982
Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism.
Orlando KA, Douglas AK, Abudu A, Wang Y, Tessier-Cloutier B, Su W, Peters A, Sherman LS, Moore R, Nguyen V, Negri GL, Colborne S, Morin GB, Kommoss F, Lang JD, Hendricks WP, Raupach EA, Pirrotte P, Huntsman DG, Trent JM, Parker JS, Raab JR, Weissman BE. Orlando KA, et al. Among authors: negri gl. Elife. 2020 Dec 23;9:e59073. doi: 10.7554/eLife.59073. Elife. 2020. PMID: 33355532 Free PMC article.
HACE1 blocks HIF1α accumulation under hypoxia in a RAC1 dependent manner.
Turgu B, Zhang F, El-Naggar A, Negri GL, Kogler M, Tortola L, Johnson F, Ng T, Li A, Yapp D, Lockwood W, Martinez D, Maris JM, Daugaard M, Penninger JM, Hughes CS, Sorensen PH. Turgu B, et al. Among authors: negri gl. Oncogene. 2021 Mar;40(11):1988-2001. doi: 10.1038/s41388-021-01680-1. Epub 2021 Feb 18. Oncogene. 2021. PMID: 33603169 Free PMC article.
Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma.
Zhang HF, Hughes CS, Li W, He JZ, Surdez D, El-Naggar AM, Cheng H, Prudova A, Delaidelli A, Negri GL, Li X, Ørum-Madsen MS, Lizardo MM, Oo HZ, Colborne S, Shyp T, Scopim-Ribeiro R, Hammond CA, Dhez AC, Langman S, Lim JKM, Kung SHY, Li A, Steino A, Daugaard M, Parker SJ, Geltink RIK, Orentas RJ, Xu LY, Morin GB, Delattre O, Dimitrov DS, Sorensen PH. Zhang HF, et al. Among authors: negri gl. Cancer Discov. 2021 Nov;11(11):2884-2903. doi: 10.1158/2159-8290.CD-20-1690. Epub 2021 May 21. Cancer Discov. 2021. PMID: 34021002 Free PMC article.
The proteome of clear cell ovarian carcinoma.
Ji JX, Cochrane DR, Negri GL, Colborne S, Spencer Miko SE, Hoang LN, Farnell D, Tessier-Cloutier B, Huvila J, Thompson E, Leung S, Chiu D, Chow C, Ta M, Köbel M, Feil L, Anglesio M, Goode EL, Bolton K, Morin GB, Huntsman DG. Ji JX, et al. Among authors: negri gl. J Pathol. 2022 Dec;258(4):325-338. doi: 10.1002/path.6006. Epub 2022 Oct 14. J Pathol. 2022. PMID: 36031730 Free PMC article.
Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma.
Topham JT, Tsang ES, Karasinska JM, Metcalfe A, Ali H, Kalloger SE, Csizmok V, Williamson LM, Titmuss E, Nielsen K, Negri GL, Spencer Miko SE, Jang GH, Denroche RE, Wong HL, O'Kane GM, Moore RA, Mungall AJ, Loree JM, Notta F, Wilson JM, Bathe OF, Tang PA, Goodwin R, Morin GB, Knox JJ, Gallinger S, Laskin J, Marra MA, Jones SJM, Schaeffer DF, Renouf DJ. Topham JT, et al. Among authors: negri gl. Nat Commun. 2022 Oct 8;13(1):5941. doi: 10.1038/s41467-022-33718-7. Nat Commun. 2022. PMID: 36209277 Free PMC article.
63 results