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Dual deletion of guanylyl cyclase-A and p38 mitogen-activated protein kinase in podocytes with aldosterone administration causes glomerular intra-capillary thrombi.
Sugioka S, Yamada H, Ishii A, Kato Y, Yamada R, Mori KP, Ohno S, Handa T, Ikushima A, Ishimura T, Osaki K, Tokudome T, Matsusaka T, Nebreda AR, Yanagita M, Yokoi H. Sugioka S, et al. Among authors: nebreda ar. Kidney Int. 2023 Sep;104(3):508-525. doi: 10.1016/j.kint.2023.06.007. Epub 2023 Jun 24. Kidney Int. 2023. PMID: 37356621
Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathway.
González L, Díaz L, Pous J, Baginski B, Duran-Corbera A, Scarpa M, Brun-Heath I, Igea A, Martin-Malpartida P, Ruiz L, Pallara C, Esguerra M, Colizzi F, Mayor-Ruiz C, Biondi RM, Soliva R, Macias MJ, Orozco M, Nebreda AR. González L, et al. Among authors: nebreda ar. Nat Commun. 2023 Jun 12;14(1):3318. doi: 10.1038/s41467-023-39051-x. Nat Commun. 2023. PMID: 37308482 Free PMC article.
The atypical CDK activator RingoA/Spy1 regulates exit from quiescence in neural stem cells.
Gonzalez L, Domingo-Muelas A, Duart-Abadia P, Nuñez M, Mikolcevic P, Llonch E, Cubillos-Rojas M, Cánovas B, Forrow SMA, Morante-Redolat JM, Fariñas I, Nebreda AR. Gonzalez L, et al. Among authors: nebreda ar. iScience. 2023 Feb 14;26(3):106202. doi: 10.1016/j.isci.2023.106202. eCollection 2023 Mar 17. iScience. 2023. PMID: 36876138 Free PMC article.
Stress signaling boosts interferon-induced gene transcription in macrophages.
Boccuni L, Podgorschek E, Schmiedeberg M, Platanitis E, Traxler P, Fischer P, Schirripa A, Novoszel P, Nebreda AR, Arthur JSC, Fortelny N, Farlik M, Sexl V, Bock C, Sibilia M, Kovarik P, Müller M, Decker T. Boccuni L, et al. Among authors: nebreda ar. Sci Signal. 2022 Dec 13;15(764):eabq5389. doi: 10.1126/scisignal.abq5389. Epub 2022 Dec 13. Sci Signal. 2022. PMID: 36512641
MK2 degradation as a sensor of signal intensity that controls stress-induced cell fate.
Gutierrez-Prat N, Cubillos-Rojas M, Cánovas B, Kuzmanic A, Gupta J, Igea A, Llonch E, Gaestel M, Nebreda AR. Gutierrez-Prat N, et al. Among authors: nebreda ar. Proc Natl Acad Sci U S A. 2021 Jul 20;118(29):e2024562118. doi: 10.1073/pnas.2024562118. Proc Natl Acad Sci U S A. 2021. PMID: 34272277 Free PMC article.
Cytokine Storm.
Gaestel M, Nebreda AR, Yaffe MB. Gaestel M, et al. Among authors: nebreda ar. N Engl J Med. 2021 Apr 22;384(16):e59. doi: 10.1056/NEJMc2036236. N Engl J Med. 2021. PMID: 33882214 No abstract available.
184 results