Neamati N - Search Results

1

Design, synthesis and structure-activity studies of rhodanine derivatives as HIV-1 integrase inhibitors.

Ramkumar K, Yarovenko VN, Nikitina AS, Zavarzin IV, Krayushkin MM, Kovalenko LV, Esqueda A, Odde S, Neamati N. Ramkumar K, et al. Among authors: neamati n. Molecules. 2010 Jun 1;15(6):3958-92. doi: 10.3390/molecules15063958. Molecules. 2010. PMID: 20657419 Free PMC article.

2

Inhibitors of human immunodeficiency virus integrase.

Pommier Y, Neamati N. Pommier Y, et al. Among authors: neamati n. Adv Virus Res. 1999;52:427-58. doi: 10.1016/s0065-3527(08)60310-3. Adv Virus Res. 1999. PMID: 10384246 Review.

3

Identification of HIV-1 integrase inhibitors via three-dimensional database searching using ASV and HIV-1 integrases as targets.

Chen IJ, Neamati N, Nicklaus MC, Orr A, Anderson L, Barchi JJ Jr, Kelley JA, Pommier Y, MacKerell AD Jr. Chen IJ, et al. Among authors: neamati n. Bioorg Med Chem. 2000 Oct;8(10):2385-98. doi: 10.1016/s0968-0896(00)00180-2. Bioorg Med Chem. 2000. PMID: 11058033

4

Structure-based HIV-1 integrase inhibitor design: a future perspective.

Neamati N. Neamati N. Expert Opin Investig Drugs. 2001 Feb;10(2):281-96. doi: 10.1517/13543784.10.2.281. Expert Opin Investig Drugs. 2001. PMID: 11178341 Review.

5

Structure-based inhibitor design targeting HIV-1 integrase.

Chen IJ, Neamati N, MacKerell AD Jr. Chen IJ, et al. Among authors: neamati n. Curr Drug Targets Infect Disord. 2002 Sep;2(3):217-34. doi: 10.2174/1568005023342380. Curr Drug Targets Infect Disord. 2002. PMID: 12462126 Review.

6

Metal-dependent inhibition of HIV-1 integrase.

Neamati N, Lin Z, Karki RG, Orr A, Cowansage K, Strumberg D, Pais GC, Voigt JH, Nicklaus MC, Winslow HE, Zhao H, Turpin JA, Yi J, Skalka AM, Burke TR Jr, Pommier Y. Neamati N, et al. J Med Chem. 2002 Dec 19;45(26):5661-70. doi: 10.1021/jm0201417. J Med Chem. 2002. PMID: 12477350

We had previously identified a series of salicylhydrazides as potent inhibitors of IN in vitro (Neamati, N.; et al. J. Med. Chem. 1998, 41, 3202-3209.). Herein, we report the design, synthesis, and antiviral activity of three novel mercaptosalicylhydrazide (MSH) der …

We had previously identified a series of salicylhydrazides as potent inhibitors of IN in vitro (Neamati, N.; et al. J. Med. Ch …

7

Dipyrimidine-based inhibitors of HIV-1 integrase.

Neamati N. Neamati N. Expert Opin Investig Drugs. 2003 Feb;12(2):289-92. doi: 10.1517/13543784.12.2.289. Expert Opin Investig Drugs. 2003. PMID: 12556222 Review. No abstract available.

8

Small-molecule HIV-1 integrase inhibitors: the 2001-2002 update.

Dayam R, Neamati N. Dayam R, et al. Among authors: neamati n. Curr Pharm Des. 2003;9(22):1789-802. doi: 10.2174/1381612033454469. Curr Pharm Des. 2003. PMID: 12871197 Review.

9

Application of CoMFA and CoMSIA 3D-QSAR and docking studies in optimization of mercaptobenzenesulfonamides as HIV-1 integrase inhibitors.

Kuo CL, Assefa H, Kamath S, Brzozowski Z, Slawinski J, Saczewski F, Buolamwini JK, Neamati N. Kuo CL, et al. Among authors: neamati n. J Med Chem. 2004 Jan 15;47(2):385-99. doi: 10.1021/jm030378i. J Med Chem. 2004. PMID: 14711310

10

De novo design and synthesis of HIV-1 integrase inhibitors.

Makhija MT, Kasliwal RT, Kulkarni VM, Neamati N. Makhija MT, et al. Among authors: neamati n. Bioorg Med Chem. 2004 May 1;12(9):2317-33. doi: 10.1016/j.bmc.2004.02.005. Bioorg Med Chem. 2004. PMID: 15080929

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