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The National COVID Cohort Collaborative (N3C): Rationale, design, infrastructure, and deployment.
Haendel MA, Chute CG, Bennett TD, Eichmann DA, Guinney J, Kibbe WA, Payne PRO, Pfaff ER, Robinson PN, Saltz JH, Spratt H, Suver C, Wilbanks J, Wilcox AB, Williams AE, Wu C, Blacketer C, Bradford RL, Cimino JJ, Clark M, Colmenares EW, Francis PA, Gabriel D, Graves A, Hemadri R, Hong SS, Hripscak G, Jiao D, Klann JG, Kostka K, Lee AM, Lehmann HP, Lingrey L, Miller RT, Morris M, Murphy SN, Natarajan K, Palchuk MB, Sheikh U, Solbrig H, Visweswaran S, Walden A, Walters KM, Weber GM, Zhang XT, Zhu RL, Amor B, Girvin AT, Manna A, Qureshi N, Kurilla MG, Michael SG, Portilla LM, Rutter JL, Austin CP, Gersing KR; N3C Consortium. Haendel MA, et al. Among authors: natarajan k. J Am Med Inform Assoc. 2021 Mar 1;28(3):427-443. doi: 10.1093/jamia/ocaa196. J Am Med Inform Assoc. 2021. PMID: 32805036 Free PMC article.
Diagnosis code assignment: models and evaluation metrics.
Perotte A, Pivovarov R, Natarajan K, Weiskopf N, Wood F, Elhadad N. Perotte A, et al. Among authors: natarajan k. J Am Med Inform Assoc. 2014 Mar-Apr;21(2):231-7. doi: 10.1136/amiajnl-2013-002159. Epub 2013 Dec 2. J Am Med Inform Assoc. 2014. PMID: 24296907 Free PMC article.
Facilitating phenotype transfer using a common data model.
Hripcsak G, Shang N, Peissig PL, Rasmussen LV, Liu C, Benoit B, Carroll RJ, Carrell DS, Denny JC, Dikilitas O, Gainer VS, Howell KM, Klann JG, Kullo IJ, Lingren T, Mentch FD, Murphy SN, Natarajan K, Pacheco JA, Wei WQ, Wiley K, Weng C. Hripcsak G, et al. Among authors: natarajan k. J Biomed Inform. 2019 Aug;96:103253. doi: 10.1016/j.jbi.2019.103253. Epub 2019 Jul 17. J Biomed Inform. 2019. PMID: 31325501 Free PMC article.
COVID-19 TestNorm: A tool to normalize COVID-19 testing names to LOINC codes.
Dong X, Li J, Soysal E, Bian J, DuVall SL, Hanchrow E, Liu H, Lynch KE, Matheny M, Natarajan K, Ohno-Machado L, Pakhomov S, Reeves RM, Sitapati AM, Abhyankar S, Cullen T, Deckard J, Jiang X, Murphy R, Xu H. Dong X, et al. Among authors: natarajan k. J Am Med Inform Assoc. 2020 Jul 1;27(9):1437-1442. doi: 10.1093/jamia/ocaa145. J Am Med Inform Assoc. 2020. PMID: 32569358 Free PMC article.
Development and validation of prediction models for mechanical ventilation, renal replacement therapy, and readmission in COVID-19 patients.
Rodriguez VA, Bhave S, Chen R, Pang C, Hripcsak G, Sengupta S, Elhadad N, Green R, Adelman J, Metitiri KS, Elias P, Groves H, Mohan S, Natarajan K, Perotte A. Rodriguez VA, et al. Among authors: natarajan k. J Am Med Inform Assoc. 2021 Jul 14;28(7):1480-1488. doi: 10.1093/jamia/ocab029. J Am Med Inform Assoc. 2021. PMID: 33706377 Free PMC article.
COVID-19 in patients with autoimmune diseases: characteristics and outcomes in a multinational network of cohorts across three countries.
Tan EH, Sena AG, Prats-Uribe A, You SC, Ahmed WU, Kostka K, Reich C, Duvall SL, Lynch KE, Matheny ME, Duarte-Salles T, Bertolin SF, Hripcsak G, Natarajan K, Falconer T, Spotnitz M, Ostropolets A, Blacketer C, Alshammari TM, Alghoul H, Alser O, Lane JCE, Dawoud DM, Shah K, Yang Y, Zhang L, Areia C, Golozar A, Recalde M, Casajust P, Jonnagaddala J, Subbian V, Vizcaya D, Lai LYH, Nyberg F, Morales DR, Posada JD, Shah NH, Gong M, Vivekanantham A, Abend A, Minty EP, Suchard M, Rijnbeek P, Ryan PB, Prieto-Alhambra D. Tan EH, et al. Among authors: natarajan k. Rheumatology (Oxford). 2021 Oct 9;60(SI):SI37-SI50. doi: 10.1093/rheumatology/keab250. Rheumatology (Oxford). 2021. PMID: 33725121 Free PMC article.
Characterizing database granularity using SNOMED-CT hierarchy.
Ostropolets A, Reich C, Ryan P, Weng C, Molinaro A, DeFalco F, Jonnagaddala J, Liaw ST, Jeon H, Park RW, Spotnitz ME, Natarajan K, Argyriou G, Kostka K, Miller R, Williams A, Minty E, Posada J, Hripcsak G. Ostropolets A, et al. Among authors: natarajan k. AMIA Annu Symp Proc. 2021 Jan 25;2020:983-992. eCollection 2020. AMIA Annu Symp Proc. 2021. PMID: 33936474 Free PMC article.
Characteristics and Outcomes of Over 300,000 Patients with COVID-19 and History of Cancer in the United States and Spain.
Roel E, Pistillo A, Recalde M, Sena AG, Fernández-Bertolín S, Aragón M, Puente D, Ahmed WU, Alghoul H, Alser O, Alshammari TM, Areia C, Blacketer C, Carter W, Casajust P, Culhane AC, Dawoud D, DeFalco F, DuVall SL, Falconer T, Golozar A, Gong M, Hester L, Hripcsak G, Tan EH, Jeon H, Jonnagaddala J, Lai LYH, Lynch KE, Matheny ME, Morales DR, Natarajan K, Nyberg F, Ostropolets A, Posada JD, Prats-Uribe A, Reich CG, Rivera DR, Schilling LM, Soerjomataram I, Shah K, Shah NH, Shen Y, Spotniz M, Subbian V, Suchard MA, Trama A, Zhang L, Zhang Y, Ryan PB, Prieto-Alhambra D, Kostka K, Duarte-Salles T. Roel E, et al. Among authors: natarajan k. Cancer Epidemiol Biomarkers Prev. 2021 Oct;30(10):1884-1894. doi: 10.1158/1055-9965.EPI-21-0266. Epub 2021 Jul 16. Cancer Epidemiol Biomarkers Prev. 2021. PMID: 34272262 Free PMC article.
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