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Identification of novel conserved Ixodes vaccine candidates; a promising role for non-secreted salivary gland proteins.
Trentelman JJA, de Vogel FA, Colstrup E, Sima R, Coumou J, Koetsveld J, Klouwens MJ, Nayak A, Ersoz J, Barriales D, Tomás-Cortázar J, Narasimhan S, Hajdusek O, Anguita J, Hovius JW. Trentelman JJA, et al. Among authors: narasimhan s. Vaccine. 2022 Dec 12;40(52):7593-7603. doi: 10.1016/j.vaccine.2022.10.032. Epub 2022 Nov 8. Vaccine. 2022. PMID: 36357287 Free article.
The Lyme disease agent exploits a tick protein to infect the mammalian host.
Ramamoorthi N, Narasimhan S, Pal U, Bao F, Yang XF, Fish D, Anguita J, Norgard MV, Kantor FS, Anderson JF, Koski RA, Fikrig E. Ramamoorthi N, et al. Among authors: narasimhan s. Nature. 2005 Jul 28;436(7050):573-7. doi: 10.1038/nature03812. Nature. 2005. PMID: 16049492 Free PMC article.
A tick mannose-binding lectin inhibitor interferes with the vertebrate complement cascade to enhance transmission of the lyme disease agent.
Schuijt TJ, Coumou J, Narasimhan S, Dai J, Deponte K, Wouters D, Brouwer M, Oei A, Roelofs JJ, van Dam AP, van der Poll T, Van't Veer C, Hovius JW, Fikrig E. Schuijt TJ, et al. Among authors: narasimhan s. Cell Host Microbe. 2011 Aug 18;10(2):136-46. doi: 10.1016/j.chom.2011.06.010. Cell Host Microbe. 2011. PMID: 21843870 Free PMC article.
A case of meningoencephalitis by the relapsing fever spirochaete Borrelia miyamotoi in Europe.
Hovius JW, de Wever B, Sohne M, Brouwer MC, Coumou J, Wagemakers A, Oei A, Knol H, Narasimhan S, Hodiamont CJ, Jahfari S, Pals ST, Horlings HM, Fikrig E, Sprong H, van Oers MH. Hovius JW, et al. Among authors: narasimhan s. Lancet. 2013 Aug 17;382(9892):658. doi: 10.1016/S0140-6736(13)61644-X. Lancet. 2013. PMID: 23953389 Free PMC article. No abstract available.
Variable Major Proteins as Targets for Specific Antibodies against Borrelia miyamotoi.
Wagemakers A, Koetsveld J, Narasimhan S, Wickel M, Deponte K, Bleijlevens B, Jahfari S, Sprong H, Karan LS, Sarksyan DS, van der Poll T, Bockenstedt LK, Bins AD, Platonov AE, Fikrig E, Hovius JW. Wagemakers A, et al. Among authors: narasimhan s. J Immunol. 2016 May 15;196(10):4185-95. doi: 10.4049/jimmunol.1600014. Epub 2016 Apr 13. J Immunol. 2016. PMID: 27076681 Free PMC article.
562 results