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Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans.
Zhu Y, Prata LGPL, Gerdes EOW, Netto JME, Pirtskhalava T, Giorgadze N, Tripathi U, Inman CL, Johnson KO, Xue A, Palmer AK, Chen T, Schaefer K, Justice JN, Nambiar AM, Musi N, Kritchevsky SB, Chen J, Khosla S, Jurk D, Schafer MJ, Tchkonia T, Kirkland JL. Zhu Y, et al. Among authors: nambiar am. EBioMedicine. 2022 Mar;77:103912. doi: 10.1016/j.ebiom.2022.103912. Epub 2022 Mar 13. EBioMedicine. 2022. PMID: 35292270 Free PMC article.
Cellular Senescence in Idiopathic Pulmonary Fibrosis.
Kellogg DL, Kellogg DL Jr, Musi N, Nambiar AM. Kellogg DL, et al. Among authors: nambiar am. Curr Mol Biol Rep. 2021;7(3):31-40. doi: 10.1007/s40610-021-00145-4. Epub 2021 Aug 12. Curr Mol Biol Rep. 2021. PMID: 34401216 Free PMC article. Review.
Senolytics dasatinib and quercetin in idiopathic pulmonary fibrosis: results of a phase I, single-blind, single-center, randomized, placebo-controlled pilot trial on feasibility and tolerability.
Nambiar A, Kellogg D 3rd, Justice J, Goros M, Gelfond J, Pascual R, Hashmi S, Masternak M, Prata L, LeBrasseur N, Limper A, Kritchevsky S, Musi N, Tchkonia T, Kirkland J. Nambiar A, et al. EBioMedicine. 2023 Apr;90:104481. doi: 10.1016/j.ebiom.2023.104481. Epub 2023 Feb 28. EBioMedicine. 2023. PMID: 36857968 Free PMC article. Clinical Trial.
Lung Microbiome in Idiopathic Pulmonary Fibrosis and Other Interstitial Lung Diseases.
Amati F, Stainer A, Mantero M, Gramegna A, Simonetta E, Suigo G, Voza A, Nambiar AM, Cariboni U, Oldham J, Molyneaux PL, Spagnolo P, Blasi F, Aliberti S. Amati F, et al. Among authors: nambiar am. Int J Mol Sci. 2022 Jan 17;23(2):977. doi: 10.3390/ijms23020977. Int J Mol Sci. 2022. PMID: 35055163 Free PMC article. Review.
Effect of Antimicrobial Therapy on Respiratory Hospitalization or Death in Adults With Idiopathic Pulmonary Fibrosis: The CleanUP-IPF Randomized Clinical Trial.
Martinez FJ, Yow E, Flaherty KR, Snyder LD, Durheim MT, Wisniewski SR, Sciurba FC, Raghu G, Brooks MM, Kim DY, Dilling DF, Criner GJ, Kim H, Belloli EA, Nambiar AM, Scholand MB, Anstrom KJ, Noth I; CleanUP-IPF Investigators of the Pulmonary Trials Cooperative. Martinez FJ, et al. Among authors: nambiar am. JAMA. 2021 May 11;325(18):1841-1851. doi: 10.1001/jama.2021.4956. JAMA. 2021. PMID: 33974018 Free PMC article. Clinical Trial.
31 results