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NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62.
Furthmann N, Bader V, Angersbach L, Blusch A, Goel S, Sánchez-Vicente A, Krause LJ, Chaban SA, Grover P, Trinkaus VA, van Well EM, Jaugstetter M, Tschulik K, Damgaard RB, Saft C, Ellrichmann G, Gold R, Koch A, Englert B, Westenberger A, Klein C, Jungbluth L, Sachse C, Behrends C, Glatzel M, Hartl FU, Nakamura K, Christine CW, Huang EJ, Tatzelt J, Winklhofer KF. Furthmann N, et al. Among authors: nakamura k. Nat Commun. 2023 Dec 19;14(1):8368. doi: 10.1038/s41467-023-44033-0. Nat Commun. 2023. PMID: 38114471 Free PMC article.
Linear ubiquitination induces NEMO phase separation to activate NF-κB signaling.
Goel S, Oliva R, Jeganathan S, Bader V, Krause LJ, Kriegler S, Stender ID, Christine CW, Nakamura K, Hoffmann JE, Winter R, Tatzelt J, Winklhofer KF. Goel S, et al. Among authors: nakamura k. Life Sci Alliance. 2023 Jan 31;6(4):e202201607. doi: 10.26508/lsa.202201607. Print 2023 Apr. Life Sci Alliance. 2023. PMID: 36720498 Free PMC article.
The behavior of alpha-synuclein in neurons.
Fortin DL, Nemani VM, Nakamura K, Edwards RH. Fortin DL, et al. Among authors: nakamura k. Mov Disord. 2010;25 Suppl 1:S21-6. doi: 10.1002/mds.22722. Mov Disord. 2010. PMID: 20187244
α-Synuclein and mitochondria: partners in crime?
Nakamura K. Nakamura K. Neurotherapeutics. 2013 Jul;10(3):391-9. doi: 10.1007/s13311-013-0182-9. Neurotherapeutics. 2013. PMID: 23512373 Free PMC article. Review.
The ubiquitin ligase parkin mediates resistance to intracellular pathogens.
Manzanillo PS, Ayres JS, Watson RO, Collins AC, Souza G, Rae CS, Schneider DS, Nakamura K, Shiloh MU, Cox JS. Manzanillo PS, et al. Among authors: nakamura k. Nature. 2013 Sep 26;501(7468):512-6. doi: 10.1038/nature12566. Epub 2013 Sep 4. Nature. 2013. PMID: 24005326 Free PMC article.
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