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Discovery of DS-9300: A Highly Potent, Selective, and Once-Daily Oral EP300/CBP Histone Acetyltransferase Inhibitor.
Kanada R, Kagoshima Y, Suzuki T, Nakamura A, Funami H, Watanabe J, Asano M, Takahashi M, Ubukata O, Suzuki K, Aikawa T, Sato K, Goto M, Setsu G, Ito K, Kihara K, Kuroha M, Kohno T, Ogiwara H, Isoyama T, Tominaga Y, Higuchi S, Naito H. Kanada R, et al. Among authors: nakamura a. J Med Chem. 2023 Jan 12;66(1):695-715. doi: 10.1021/acs.jmedchem.2c01641. Epub 2022 Dec 26. J Med Chem. 2023. PMID: 36572866
Renadirsen, a Novel 2'OMeRNA/ENA® Chimera Antisense Oligonucleotide, Induces Robust Exon 45 Skipping for Dystrophin In Vivo.
Ito K, Takakusa H, Kakuta M, Kanda A, Takagi N, Nagase H, Watanabe N, Asano D, Goda R, Masuda T, Nakamura A, Onishi Y, Onoda T, Koizumi M, Takeshima Y, Matsuo M, Takaishi K. Ito K, et al. Among authors: nakamura a. Curr Issues Mol Biol. 2021 Sep 25;43(3):1267-1281. doi: 10.3390/cimb43030090. Curr Issues Mol Biol. 2021. PMID: 34698059 Free PMC article.
Not all 2',4'-bridged modifications stabilize DNA/RNA duplexes.
Akita T, Tomita-Sudo E, Itoh S, Sakimoto N, Masuda T, Nakamura A, Onishi Y, Koizumi M, Kawakami J. Akita T, et al. Among authors: nakamura a. Nucleosides Nucleotides Nucleic Acids. 2024;43(1):57-64. doi: 10.1080/15257770.2023.2232414. Epub 2023 Jul 9. Nucleosides Nucleotides Nucleic Acids. 2024. PMID: 37424260
Japanese Society for infection prevention and control guide to Clostridioides difficile infection prevention and control.
Kunishima H, Ichiki K, Ohge H, Sakamoto F, Sato Y, Suzuki H, Nakamura A, Fujimura S, Matsumoto K, Mikamo H, Mizutani T, Morinaga Y, Mori M, Yamagishi Y, Yoshizawa S. Kunishima H, et al. Among authors: nakamura a. J Infect Chemother. 2024 May 5:S1341-321X(24)00102-8. doi: 10.1016/j.jiac.2024.03.018. Online ahead of print. J Infect Chemother. 2024. PMID: 38714273 No abstract available.
A comparative study of the effects of imeglimin add-on or metformin dose escalation on glycaemic variability in subjects with type 2 diabetes treated with low-dose metformin (MEGMI-CGM study).
Takahashi A, Nomoto H, Onishi K, Manda S, Miya A, Kameda H, Nakamura A, Atsumi T. Takahashi A, et al. Among authors: nakamura a. Diabetes Obes Metab. 2024 May 3. doi: 10.1111/dom.15639. Online ahead of print. Diabetes Obes Metab. 2024. PMID: 38699794 No abstract available.
3,777 results