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The novel potent TEAD inhibitor, K-975, inhibits YAP1/TAZ-TEAD protein-protein interactions and exerts an anti-tumor effect on malignant pleural mesothelioma.
Kaneda A, Seike T, Danjo T, Nakajima T, Otsubo N, Yamaguchi D, Tsuji Y, Hamaguchi K, Yasunaga M, Nishiya Y, Suzuki M, Saito JI, Yatsunami R, Nakamura S, Sekido Y, Mori K. Kaneda A, et al. Among authors: nakajima t. Am J Cancer Res. 2020 Dec 1;10(12):4399-4415. eCollection 2020. Am J Cancer Res. 2020. PMID: 33415007 Free PMC article.
siRNA potency enhancement via chemical modifications of nucleotide bases at the 5'-end of the siRNA guide strand.
Shinohara F, Oashi T, Harumoto T, Nishikawa T, Takayama Y, Miyagi H, Takahashi Y, Nakajima T, Sawada T, Koda Y, Makino A, Sato A, Hamaguchi K, Suzuki M, Yamamoto J, Tomari Y, Saito JI. Shinohara F, et al. Among authors: nakajima t. RNA. 2021 Feb;27(2):163-173. doi: 10.1261/rna.073783.119. Epub 2020 Nov 11. RNA. 2021. PMID: 33177188 Free PMC article.
Highly Sensitive Bioluminescent Probe for Thiol Detection in Living Cells.
Hemmi M, Ikeda Y, Shindo Y, Nakajima T, Nishiyama S, Oka K, Sato M, Hiruta Y, Citterio D, Suzuki K. Hemmi M, et al. Among authors: nakajima t. Chem Asian J. 2018 Mar 16;13(6):648-655. doi: 10.1002/asia.201701774. Epub 2018 Feb 21. Chem Asian J. 2018. PMID: 29359483
Rational conversion of chromophore selectivity of cyanobacteriochromes to accept mammalian intrinsic biliverdin.
Fushimi K, Miyazaki T, Kuwasaki Y, Nakajima T, Yamamoto T, Suzuki K, Ueda Y, Miyake K, Takeda Y, Choi JH, Kawagishi H, Park EY, Ikeuchi M, Sato M, Narikawa R. Fushimi K, et al. Among authors: nakajima t. Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8301-8309. doi: 10.1073/pnas.1818836116. Epub 2019 Apr 4. Proc Natl Acad Sci U S A. 2019. PMID: 30948637 Free PMC article.
5,891 results