Naito H - Search Results

1

4-Pyridone-3-carboxylic acid as a benzoic acid bioisostere: Design, synthesis, and evaluation of EP300/CBP histone acetyltransferase inhibitors.

Kanada R, Suzuki T, Murata T, Miyazaki M, Shimada T, Kuroha M, Minami M, Higuchi S, Tominaga Y, Naito H. Kanada R, et al. Among authors: naito h. Bioorg Med Chem Lett. 2021 Nov 1;51:128358. doi: 10.1016/j.bmcl.2021.128358. Epub 2021 Sep 15. Bioorg Med Chem Lett. 2021. PMID: 34534674

2

Syntheses and differentiating action of vitamin D endoperoxides. Singlet oxygen adducts of vitamin D derivatives in human myeloid leukemia cells (HL-60).

Yamada S, Yamamoto K, Naito H, Suzuki T, Ohmori M, Takayama H, Shiina Y, Miyaura C, Tanaka H, Abe E, et al. Yamada S, et al. Among authors: naito h. J Med Chem. 1985 Sep;28(9):1148-53. doi: 10.1021/jm00147a005. J Med Chem. 1985. PMID: 2993611

3

Synthesis and antitumor activity of novel pyrimidinyl pyrazole derivatives. II. Optimization of the phenylpiperazine moiety of 1-[5-methyl-1-(2-pyrimidinyl)-4-pyrazolyl]-3-phenylpiperazinyl-1-trans-propenes.

Naito H, Ohsuki S, Sugimori M, Atsumi R, Minami M, Nakamura Y, Ishii M, Hirotani K, Kumazawa E, Ejima A. Naito H, et al. Chem Pharm Bull (Tokyo). 2002 Apr;50(4):453-62. doi: 10.1248/cpb.50.453. Chem Pharm Bull (Tokyo). 2002. PMID: 11963990 Free article.

4

Synthesis and mechanism of action of novel pyrimidinyl pyrazole derivatives possessing antiproliferative activity.

Ohki H, Hirotani K, Naito H, Ohsuki S, Minami M, Ejima A, Koiso Y, Hashimoto Y. Ohki H, et al. Among authors: naito h. Bioorg Med Chem Lett. 2002 Nov 4;12(21):3191-3. doi: 10.1016/s0960-894x(02)00568-1. Bioorg Med Chem Lett. 2002. PMID: 12372531

5

Synthesis and antitumor activity of novel pyrimidinyl pyrazole derivatives. III. Synthesis and antitumor activity of 3-phenylpiperazinyl-1-trans-propenes.

Naito H, Ohsuki S, Atsumi R, Minami M, Mochizuki M, Hirotani K, Kumazawa E, Ejima A. Naito H, et al. Chem Pharm Bull (Tokyo). 2005 Feb;53(2):153-63. doi: 10.1248/cpb.53.153. Chem Pharm Bull (Tokyo). 2005. PMID: 15684512 Free article.

6

Design, synthesis, and biological activity of piperidine diamine derivatives as factor Xa inhibitor.

Mochizuki A, Nakamoto Y, Naito H, Uoto K, Ohta T. Mochizuki A, et al. Among authors: naito h. Bioorg Med Chem Lett. 2008 Jan 15;18(2):782-7. doi: 10.1016/j.bmcl.2007.11.037. Epub 2007 Nov 17. Bioorg Med Chem Lett. 2008. PMID: 18039572

7

Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part I: exploration of 5-6 fused rings as alternative S1 moieties.

Yoshikawa K, Yokomizo A, Naito H, Haginoya N, Kobayashi S, Yoshino T, Nagata T, Mochizuki A, Osanai K, Watanabe K, Kanno H, Ohta T. Yoshikawa K, et al. Among authors: naito h. Bioorg Med Chem. 2009 Dec 15;17(24):8206-20. doi: 10.1016/j.bmc.2009.10.023. Epub 2009 Oct 31. Bioorg Med Chem. 2009. PMID: 19884015

8

Design, synthesis and SAR of novel ethylenediamine and phenylenediamine derivatives as factor Xa inhibitors.

Yoshikawa K, Yoshino T, Yokomizo Y, Uoto K, Naito H, Kawakami K, Mochizuki A, Nagata T, Suzuki M, Kanno H, Takemura M, Ohta T. Yoshikawa K, et al. Among authors: naito h. Bioorg Med Chem Lett. 2011 Apr 1;21(7):2133-40. doi: 10.1016/j.bmcl.2011.01.132. Epub 2011 Feb 1. Bioorg Med Chem Lett. 2011. PMID: 21345673

9

Discovery of novel dihydroimidazothiazole derivatives as p53-MDM2 protein-protein interaction inhibitors: synthesis, biological evaluation and structure-activity relationships.

Miyazaki M, Kawato H, Naito H, Ikeda M, Miyazaki M, Kitagawa M, Seki T, Fukutake S, Aonuma M, Soga T. Miyazaki M, et al. Among authors: naito h. Bioorg Med Chem Lett. 2012 Oct 15;22(20):6338-42. doi: 10.1016/j.bmcl.2012.08.086. Epub 2012 Aug 30. Bioorg Med Chem Lett. 2012. PMID: 22995624

10

Lead optimization of novel p53-MDM2 interaction inhibitors possessing dihydroimidazothiazole scaffold.

Miyazaki M, Naito H, Sugimoto Y, Kawato H, Okayama T, Shimizu H, Miyazaki M, Kitagawa M, Seki T, Fukutake S, Aonuma M, Soga T. Miyazaki M, et al. Among authors: naito h. Bioorg Med Chem Lett. 2013 Feb 1;23(3):728-32. doi: 10.1016/j.bmcl.2012.11.091. Epub 2012 Dec 1. Bioorg Med Chem Lett. 2013. PMID: 23266121

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