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209 results

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TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase.
Liu G, Haw TJ, Starkey MR, Philp AM, Pavlidis S, Nalkurthi C, Nair PM, Gomez HM, Hanish I, Hsu AC, Hortle E, Pickles S, Rojas-Quintero J, Estepar RSJ, Marshall JE, Kim RY, Collison AM, Mattes J, Idrees S, Faiz A, Hansbro NG, Fukui R, Murakami Y, Cheng HS, Tan NS, Chotirmall SH, Horvat JC, Foster PS, Oliver BG, Polverino F, Ieni A, Monaco F, Caramori G, Sohal SS, Bracke KR, Wark PA, Adcock IM, Miyake K, Sin DD, Hansbro PM. Liu G, et al. Among authors: nair pm. Nat Commun. 2023 Nov 14;14(1):7349. doi: 10.1038/s41467-023-42913-z. Nat Commun. 2023. PMID: 37963864 Free PMC article.
A pathogenic role for tumor necrosis factor-related apoptosis-inducing ligand in chronic obstructive pulmonary disease.
Haw TJ, Starkey MR, Nair PM, Pavlidis S, Liu G, Nguyen DH, Hsu AC, Hanish I, Kim RY, Collison AM, Inman MD, Wark PA, Foster PS, Knight DA, Mattes J, Yagita H, Adcock IM, Horvat JC, Hansbro PM. Haw TJ, et al. Among authors: nair pm. Mucosal Immunol. 2016 Jul;9(4):859-72. doi: 10.1038/mi.2015.111. Epub 2015 Nov 11. Mucosal Immunol. 2016. PMID: 26555706 Free article.
Toll-like receptor 2 and 4 have opposing roles in the pathogenesis of cigarette smoke-induced chronic obstructive pulmonary disease.
Haw TJ, Starkey MR, Pavlidis S, Fricker M, Arthurs AL, Nair PM, Liu G, Hanish I, Kim RY, Foster PS, Horvat JC, Adcock IM, Hansbro PM. Haw TJ, et al. Among authors: nair pm. Am J Physiol Lung Cell Mol Physiol. 2018 Feb 1;314(2):L298-L317. doi: 10.1152/ajplung.00154.2017. Epub 2017 Oct 12. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 29025711 Free PMC article.
IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis.
Starkey MR, Plank MW, Casolari P, Papi A, Pavlidis S, Guo Y, Cameron GJM, Haw TJ, Tam A, Obiedat M, Donovan C, Hansbro NG, Nguyen DH, Nair PM, Kim RY, Horvat JC, Kaiko GE, Durum SK, Wark PA, Sin DD, Caramori G, Adcock IM, Foster PS, Hansbro PM. Starkey MR, et al. Among authors: nair pm. Eur Respir J. 2019 Jul 18;54(1):1800174. doi: 10.1183/13993003.00174-2018. Print 2019 Jul. Eur Respir J. 2019. PMID: 31196943 Free PMC article.
Necroptosis Signaling Promotes Inflammation, Airway Remodeling, and Emphysema in Chronic Obstructive Pulmonary Disease.
Lu Z, Van Eeckhoutte HP, Liu G, Nair PM, Jones B, Gillis CM, Nalkurthi BC, Verhamme F, Buyle-Huybrecht T, Vandenabeele P, Vanden Berghe T, Brusselle GG, Horvat JC, Murphy JM, Wark PA, Bracke KR, Fricker M, Hansbro PM. Lu Z, et al. Among authors: nair pm. Am J Respir Crit Care Med. 2021 Sep 15;204(6):667-681. doi: 10.1164/rccm.202009-3442OC. Am J Respir Crit Care Med. 2021. PMID: 34133911
Airway and parenchymal transcriptomics in a novel model of asthma and COPD overlap.
Tu X, Kim RY, Brown AC, de Jong E, Jones-Freeman B, Ali MK, Gomez HM, Budden KF, Starkey MR, Cameron GJM, Loering S, Nguyen DH, Nair PM, Haw TJ, Alemao CA, Faiz A, Tay HL, Wark PAB, Knight DA, Foster PS, Bosco A, Horvat JC, Hansbro PM, Donovan C. Tu X, et al. Among authors: nair pm. J Allergy Clin Immunol. 2022 Oct;150(4):817-829.e6. doi: 10.1016/j.jaci.2022.04.032. Epub 2022 May 25. J Allergy Clin Immunol. 2022. PMID: 35643377
Fibulin-1 regulates the pathogenesis of tissue remodeling in respiratory diseases.
Liu G, Cooley MA, Jarnicki AG, Hsu AC, Nair PM, Haw TJ, Fricker M, Gellatly SL, Kim RY, Inman MD, Tjin G, Wark PA, Walker MM, Horvat JC, Oliver BG, Argraves WS, Knight DA, Burgess JK, Hansbro PM. Liu G, et al. Among authors: nair pm. JCI Insight. 2016 Jun 16;1(9):e86380. doi: 10.1172/jci.insight.86380. JCI Insight. 2016. PMID: 27398409 Free PMC article.
209 results