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Myelinated axons are the primary target of hemin-mediated oxidative damage in a model of the central nervous system.
Exp Neurol. 2022 Aug;354:114113. doi: 10.1016/j.expneurol.2022.114113. Epub 2022 May 13.
Exp Neurol. 2022.
PMID: 35569511
Free article.
SARM1 Depletion Slows Axon Degeneration in a CNS Model of Neurotropic Viral Infection.
Crawford CL, Antoniou C, Komarek L, Schultz V, Donald CL, Montague P, Barnett SC, Linington C, Willison HJ, Kohl A, Coleman MP, Edgar JM.
Crawford CL, et al.
Front Mol Neurosci. 2022 Apr 13;15:860410. doi: 10.3389/fnmol.2022.860410. eCollection 2022.
Front Mol Neurosci. 2022.
PMID: 35493328
Free PMC article.
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Neuronal cholesterol synthesis is essential for repair of chronically demyelinated lesions in mice.
Berghoff SA, Spieth L, Sun T, Hosang L, Depp C, Sasmita AO, Vasileva MH, Scholz P, Zhao Y, Krueger-Burg D, Wichert S, Brown ER, Michail K, Nave KA, Bonn S, Odoardi F, Rossner M, Ischebeck T, Edgar JM, Saher G.
Berghoff SA, et al.
Cell Rep. 2021 Oct 26;37(4):109889. doi: 10.1016/j.celrep.2021.109889.
Cell Rep. 2021.
PMID: 34706227
Free article.
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Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis.
Berghoff SA, Spieth L, Sun T, Hosang L, Schlaphoff L, Depp C, Düking T, Winchenbach J, Neuber J, Ewers D, Scholz P, van der Meer F, Cantuti-Castelvetri L, Sasmita AO, Meschkat M, Ruhwedel T, Möbius W, Sankowski R, Prinz M, Huitinga I, Sereda MW, Odoardi F, Ischebeck T, Simons M, Stadelmann-Nessler C, Edgar JM, Nave KA, Saher G.
Berghoff SA, et al.
Nat Neurosci. 2021 Jan;24(1):47-60. doi: 10.1038/s41593-020-00757-6. Epub 2020 Dec 21.
Nat Neurosci. 2021.
PMID: 33349711
Free PMC article.
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An in vitro model for studying CNS white matter: functional properties and experimental approaches.
Bijland S, Thomson G, Euston M, Michail K, Thümmler K, Mücklisch S, Crawford CL, Barnett SC, McLaughlin M, Anderson TJ, Linington C, Brown ER, Kalkman ER, Edgar JM.
Bijland S, et al.
F1000Res. 2019 Jan 29;8:117. doi: 10.12688/f1000research.16802.1. eCollection 2019.
F1000Res. 2019.
PMID: 31069065
Free PMC article.
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Zika virus tropism and interactions in myelinating neural cell cultures: CNS cells and myelin are preferentially affected.
Cumberworth SL, Barrie JA, Cunningham ME, de Figueiredo DPG, Schultz V, Wilder-Smith AJ, Brennan B, Pena LJ, Freitas de Oliveira França R, Linington C, Barnett SC, Willison HJ, Kohl A, Edgar JM.
Cumberworth SL, et al.
Acta Neuropathol Commun. 2017 Jun 23;5(1):50. doi: 10.1186/s40478-017-0450-8.
Acta Neuropathol Commun. 2017.
PMID: 28645311
Free PMC article.
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