N'Guyen CH - Search Results

1

Polyheteroaryl Oxazole/Pyridine-Based Compounds Selected in Vitro as G-Quadruplex Ligands Inhibit Rock Kinase and Exhibit Antiproliferative Activity.

Verga D, N'Guyen CH, Dakir M, Coll JL, Teulade-Fichou MP, Molla A. Verga D, et al. Among authors: n guyen ch. J Med Chem. 2018 Dec 13;61(23):10502-10518. doi: 10.1021/acs.jmedchem.8b01023. Epub 2018 Dec 3. J Med Chem. 2018. PMID: 30457335

2

An acyclic oligoheteroaryle that discriminates strongly between diverse G-quadruplex topologies.

Hamon F, Largy E, Guédin-Beaurepaire A, Rouchon-Dagois M, Sidibe A, Monchaud D, Mergny JL, Riou JF, Nguyen CH, Teulade-Fichou MP. Hamon F, et al. Angew Chem Int Ed Engl. 2011 Sep 5;50(37):8745-9. doi: 10.1002/anie.201103422. Epub 2011 Aug 2. Angew Chem Int Ed Engl. 2011. PMID: 21812083 No abstract available.

3

Discovery of benzo[e]pyridoindolones as kinase inhibitors that disrupt mitosis exit while erasing AMPK-Thr172 phosphorylation on the spindle.

Le LT, Couvet M, Favier B, Coll JL, Nguyen CH, Molla A. Le LT, et al. Oncotarget. 2015 Sep 8;6(26):22152-66. doi: 10.18632/oncotarget.4158. Oncotarget. 2015. PMID: 26247630 Free PMC article.

4

Hydrosoluble benzo[e]pyridoindolones as potent inhibitors of aurora kinases.

Le LT, Vu HL, Naud-Martin D, Bombled M, Nguyen CH, Molla A. Le LT, et al. ChemMedChem. 2013 Feb;8(2):289-96. doi: 10.1002/cmdc.201200479. Epub 2012 Dec 28. ChemMedChem. 2013. PMID: 23281044

5

In vitro high throughput screening, what next? Lessons from the screening for aurora kinase inhibitors.

Hoang TM, Vu HL, Le LT, Nguyen CH, Molla A. Hoang TM, et al. Biology (Basel). 2014 Feb 27;3(1):167-75. doi: 10.3390/biology3010167. Biology (Basel). 2014. PMID: 24833340 Free PMC article.

6

Multi-kinase inhibitor C1 triggers mitotic catastrophe of glioma stem cells mainly through MELK kinase inhibition.

Minata M, Gu C, Joshi K, Nakano-Okuno M, Hong C, Nguyen CH, Kornblum HI, Molla A, Nakano I. Minata M, et al. PLoS One. 2014 Apr 16;9(4):e92546. doi: 10.1371/journal.pone.0092546. eCollection 2014. PLoS One. 2014. PMID: 24739874 Free PMC article.

7

Benzo[e]pyridoindoles, novel inhibitors of the aurora kinases.

Hoang TM, Favier B, Valette A, Barette C, Nguyen CH, Lafanechère L, Grierson DS, Dimitrov S, Molla A. Hoang TM, et al. Cell Cycle. 2009 Mar 1;8(5):765-72. doi: 10.4161/cc.8.5.7879. Epub 2009 Mar 18. Cell Cycle. 2009. PMID: 19221479 Free PMC article.

8

Basal aurora kinase B activity is sufficient for histone H3 phosphorylation in prophase.

Le LT, Vu HL, Nguyen CH, Molla A. Le LT, et al. Biol Open. 2013 Feb 14;2(4):379-86. doi: 10.1242/bio.20133079. Print 2013 Apr 15. Biol Open. 2013. PMID: 23616922 Free PMC article.

9

4-Benzyl and 4-benzoyl-3-dimethylaminopyridin-2(1H)-ones: in vitro evaluation of new C-3-amino-substituted and C-5,6-alkyl-substituted analogues against clinically important HIV mutant strains.

Benjahad A, Croisy M, Monneret C, Bisagni E, Mabire D, Coupa S, Poncelet A, Csoka I, Guillemont J, Meyer C, Andries K, Pauwels R, de Béthune MP, Himmel DM, Das K, Arnold E, Nguyen CH, Grierson DS. Benjahad A, et al. J Med Chem. 2005 Mar 24;48(6):1948-64. doi: 10.1021/jm0408621. J Med Chem. 2005. PMID: 15771439

10

Synthesis and antitumor activity of 1-[[(dialkylamino)alkyl]amino]-4-methyl-5H-pyrido[4,3-b]benzo[e]- and -benzo[g])indoles. A new class of antineoplastic agents.

Nguyen CH, Lhoste JM, Lavelle F, Bissery MC, Bisagni E. Nguyen CH, et al. J Med Chem. 1990 May;33(5):1519-28. doi: 10.1021/jm00167a037. J Med Chem. 1990. PMID: 2329575

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