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Novel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's disease.
Chalupova K, Korabecny J, Bartolini M, Monti B, Lamba D, Caliandro R, Pesaresi A, Brazzolotto X, Gastellier AJ, Nachon F, Pejchal J, Jarosova M, Hepnarova V, Jun D, Hrabinova M, Dolezal R, Zdarova Karasova J, Mzik M, Kristofikova Z, Misik J, Muckova L, Jost P, Soukup O, Benkova M, Setnicka V, Habartova L, Chvojkova M, Kleteckova L, Vales K, Mezeiova E, Uliassi E, Valis M, Nepovimova E, Bolognesi ML, Kuca K. Chalupova K, et al. Among authors: mzik m. Eur J Med Chem. 2019 Apr 15;168:491-514. doi: 10.1016/j.ejmech.2019.02.021. Epub 2019 Feb 27. Eur J Med Chem. 2019. PMID: 30851693
An HPLC-MS method for the quantification of new acetylcholinesterase inhibitor PC 48 (7-MEOTA-donepezil like compound) in rat plasma: Application to a pharmacokinetic study.
Mzik M, Korabecny J, Nepovimova E, Voříšek V, Palička V, Kuca K, Zdarova Karasova J. Mzik M, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 May 1;1020:85-9. doi: 10.1016/j.jchromb.2016.02.038. Epub 2016 Mar 16. J Chromatogr B Analyt Technol Biomed Life Sci. 2016. PMID: 27030895
The New Acetylcholinesterase Inhibitors PC-37 and PC-48 (7-Methoxytacrine-Donepezil-Like Compounds): Characterization of Their Metabolites in Human Liver Microsomes, Pharmacokinetics and In Vivo Formation of the Major Metabolites in Rats.
Zdarova Karasova J, Mzik M, Hroch M, Korabecny J, Nepovimova E, Vorisek V, Palicka V, Kuca K. Zdarova Karasova J, et al. Among authors: mzik m. Basic Clin Pharmacol Toxicol. 2018 Apr;122(4):373-382. doi: 10.1111/bcpt.12922. Epub 2017 Dec 15. Basic Clin Pharmacol Toxicol. 2018. PMID: 29067789 Free article.
1-Benzyl-4-methylpiperidinyl moiety in donepezil: The priority ticket across the blood-brain-barrier in rats.
Zdarova Karasova J, Sestak V, Korabecny J, Mezeiova E, Palicka V, Kuca K, Mzik M. Zdarova Karasova J, et al. Among authors: mzik m. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Aug 15;1092:350-358. doi: 10.1016/j.jchromb.2018.06.034. Epub 2018 Jun 18. J Chromatogr B Analyt Technol Biomed Life Sci. 2018. PMID: 29936371 No abstract available.
Effect of mirtazapine on rat bone tissue after orchidectomy.
Fekete S, Simko J, Mzik M, Karesova I, Zivna H, Pavlíková L, Palicka V. Fekete S, et al. Among authors: mzik m. Pharmacology. 2015;95(3-4):166-72. doi: 10.1159/000380953. Epub 2015 Apr 2. Pharmacology. 2015. PMID: 25871861
15 results